Human Infection Challenge Studies: a Test for the Social Value Criterion of Research Ethics
ABSTRACT Human infection challenge studies involving the intentional infection of research participants with a disease-causing agent have recently been suggested as a means to speed up the search for a vaccine for the ongoing coronavirus disease 2019 (COVID-19) outbreak. Calls for challenge studies,...
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American Society for Microbiology
2020
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oai:doaj.org-article:07080868621542e684c08617d85ec64d2021-11-15T15:30:52ZHuman Infection Challenge Studies: a Test for the Social Value Criterion of Research Ethics10.1128/mSphere.00669-202379-5042https://doaj.org/article/07080868621542e684c08617d85ec64d2020-08-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mSphere.00669-20https://doaj.org/toc/2379-5042ABSTRACT Human infection challenge studies involving the intentional infection of research participants with a disease-causing agent have recently been suggested as a means to speed up the search for a vaccine for the ongoing coronavirus disease 2019 (COVID-19) outbreak. Calls for challenge studies, however, rely on the expected social value of these studies. This value represents more than the simple possibility that a successful study will lead to the rapid development and dissemination of vaccines but also some expectation that this will actually occur. I show how this expectation may not be realistic in the current political moment and offer potential ways to make sure that any challenge trials that arise actually achieve their goals.Nicholas G. EvansAmerican Society for MicrobiologyarticleCOVID-19challenge studiescoronavirusglobal healthresearch ethicsMicrobiologyQR1-502ENmSphere, Vol 5, Iss 4 (2020) |
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COVID-19 challenge studies coronavirus global health research ethics Microbiology QR1-502 |
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COVID-19 challenge studies coronavirus global health research ethics Microbiology QR1-502 Nicholas G. Evans Human Infection Challenge Studies: a Test for the Social Value Criterion of Research Ethics |
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ABSTRACT Human infection challenge studies involving the intentional infection of research participants with a disease-causing agent have recently been suggested as a means to speed up the search for a vaccine for the ongoing coronavirus disease 2019 (COVID-19) outbreak. Calls for challenge studies, however, rely on the expected social value of these studies. This value represents more than the simple possibility that a successful study will lead to the rapid development and dissemination of vaccines but also some expectation that this will actually occur. I show how this expectation may not be realistic in the current political moment and offer potential ways to make sure that any challenge trials that arise actually achieve their goals. |
format |
article |
author |
Nicholas G. Evans |
author_facet |
Nicholas G. Evans |
author_sort |
Nicholas G. Evans |
title |
Human Infection Challenge Studies: a Test for the Social Value Criterion of Research Ethics |
title_short |
Human Infection Challenge Studies: a Test for the Social Value Criterion of Research Ethics |
title_full |
Human Infection Challenge Studies: a Test for the Social Value Criterion of Research Ethics |
title_fullStr |
Human Infection Challenge Studies: a Test for the Social Value Criterion of Research Ethics |
title_full_unstemmed |
Human Infection Challenge Studies: a Test for the Social Value Criterion of Research Ethics |
title_sort |
human infection challenge studies: a test for the social value criterion of research ethics |
publisher |
American Society for Microbiology |
publishDate |
2020 |
url |
https://doaj.org/article/07080868621542e684c08617d85ec64d |
work_keys_str_mv |
AT nicholasgevans humaninfectionchallengestudiesatestforthesocialvaluecriterionofresearchethics |
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