Human Infection Challenge Studies: a Test for the Social Value Criterion of Research Ethics

ABSTRACT Human infection challenge studies involving the intentional infection of research participants with a disease-causing agent have recently been suggested as a means to speed up the search for a vaccine for the ongoing coronavirus disease 2019 (COVID-19) outbreak. Calls for challenge studies,...

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Autor principal: Nicholas G. Evans
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Lenguaje:EN
Publicado: American Society for Microbiology 2020
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Acceso en línea:https://doaj.org/article/07080868621542e684c08617d85ec64d
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spelling oai:doaj.org-article:07080868621542e684c08617d85ec64d2021-11-15T15:30:52ZHuman Infection Challenge Studies: a Test for the Social Value Criterion of Research Ethics10.1128/mSphere.00669-202379-5042https://doaj.org/article/07080868621542e684c08617d85ec64d2020-08-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mSphere.00669-20https://doaj.org/toc/2379-5042ABSTRACT Human infection challenge studies involving the intentional infection of research participants with a disease-causing agent have recently been suggested as a means to speed up the search for a vaccine for the ongoing coronavirus disease 2019 (COVID-19) outbreak. Calls for challenge studies, however, rely on the expected social value of these studies. This value represents more than the simple possibility that a successful study will lead to the rapid development and dissemination of vaccines but also some expectation that this will actually occur. I show how this expectation may not be realistic in the current political moment and offer potential ways to make sure that any challenge trials that arise actually achieve their goals.Nicholas G. EvansAmerican Society for MicrobiologyarticleCOVID-19challenge studiescoronavirusglobal healthresearch ethicsMicrobiologyQR1-502ENmSphere, Vol 5, Iss 4 (2020)
institution DOAJ
collection DOAJ
language EN
topic COVID-19
challenge studies
coronavirus
global health
research ethics
Microbiology
QR1-502
spellingShingle COVID-19
challenge studies
coronavirus
global health
research ethics
Microbiology
QR1-502
Nicholas G. Evans
Human Infection Challenge Studies: a Test for the Social Value Criterion of Research Ethics
description ABSTRACT Human infection challenge studies involving the intentional infection of research participants with a disease-causing agent have recently been suggested as a means to speed up the search for a vaccine for the ongoing coronavirus disease 2019 (COVID-19) outbreak. Calls for challenge studies, however, rely on the expected social value of these studies. This value represents more than the simple possibility that a successful study will lead to the rapid development and dissemination of vaccines but also some expectation that this will actually occur. I show how this expectation may not be realistic in the current political moment and offer potential ways to make sure that any challenge trials that arise actually achieve their goals.
format article
author Nicholas G. Evans
author_facet Nicholas G. Evans
author_sort Nicholas G. Evans
title Human Infection Challenge Studies: a Test for the Social Value Criterion of Research Ethics
title_short Human Infection Challenge Studies: a Test for the Social Value Criterion of Research Ethics
title_full Human Infection Challenge Studies: a Test for the Social Value Criterion of Research Ethics
title_fullStr Human Infection Challenge Studies: a Test for the Social Value Criterion of Research Ethics
title_full_unstemmed Human Infection Challenge Studies: a Test for the Social Value Criterion of Research Ethics
title_sort human infection challenge studies: a test for the social value criterion of research ethics
publisher American Society for Microbiology
publishDate 2020
url https://doaj.org/article/07080868621542e684c08617d85ec64d
work_keys_str_mv AT nicholasgevans humaninfectionchallengestudiesatestforthesocialvaluecriterionofresearchethics
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