Structure-Function Relationship of the Disintegrin Family: Sequence Signature and Integrin Interaction

Disintegrins are small cysteine-rich proteins found in a variety of snake venom. These proteins selectively modulate integrin function, heterodimeric receptors involved in cell-cell and cell-matrix interaction that are widely studied as therapeutic targets. Snake venom disintegrins emerged from the...

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Bibliographic Details
Main Authors: Ariana A. Vasconcelos, Jorge C. Estrada, Victor David, Luciana S. Wermelinger, Fabio C. L. Almeida, Russolina B. Zingali
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
NMR
Online Access:https://doaj.org/article/070e4d89500c4200a16f6a897ef11ad2
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