FTIR-based Fingerprinting and Chemometrics for Rapid Investigation of Antioxidant Activity from <i>Syzygium polyanthum</i> Extracts

Syzygium polyanthum, known as salam in Indonesia, which is rich in phenolics compounds with high antioxidant activity. In this study, we performed the determination of total phenolics and characterization of the antioxidant activity of S. polyanthum leaves extracts using the FTIR-based fingerprintin...

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Autores principales:	Eti Rohaeti, Fadila Karunina, Mohamad Rafi
Formato:	article
Lenguaje:	EN
Publicado:	Department of Chemistry, Universitas Gadjah Mada 2020
Materias:	antioxidant chemometrics fingerprinting ftir s. polyanthum Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/0714007cd234453da079d3ef87e5657e
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spelling	oai:doaj.org-article:0714007cd234453da079d3ef87e5657e2021-12-02T14:02:46ZFTIR-based Fingerprinting and Chemometrics for Rapid Investigation of Antioxidant Activity from <i>Syzygium polyanthum</i> Extracts1411-94202460-157810.22146/ijc.54577https://doaj.org/article/0714007cd234453da079d3ef87e5657e2020-10-01T00:00:00Zhttps://jurnal.ugm.ac.id/ijc/article/view/54577https://doaj.org/toc/1411-9420https://doaj.org/toc/2460-1578Syzygium polyanthum, known as salam in Indonesia, which is rich in phenolics compounds with high antioxidant activity. In this study, we performed the determination of total phenolics and characterization of the antioxidant activity of S. polyanthum leaves extracts using the FTIR-based fingerprinting technique. The extracts of S. polyanthum in water, ethanol, and ethanol-water (30, 50, and 70%) were measured for their antioxidant activity, total phenolics, and FTIR spectra. The antioxidant activity of S. polyanthum extract with different solvent extraction showed the highest antioxidant activity and total phenolic content is 70% and 50% ethanolic extract, respectively. The FTIR spectrum of each extract showed identical FTIR spectra patterns. According to their different solvent extraction, S. polyanthum extract could be grouped based on FTIR spectra using principal component analysis. Correlation between the functional group in the FTIR spectra with IC50 from S. polyanthum extract was analyzed using partial least square (PLS). The PLS analysis results showed that O–H, C–H sp3, C=O, C=C, C-O, and C–H aromatic are the main functional groups contributed to the antioxidant activity of S. polyanthum extract. FTIR-based fingerprinting combined with chemometrics could be used to classify different extracts of S. polyanthum and predicted functional groups having a significant contribution to antioxidant activity.Eti RohaetiFadila KaruninaMohamad RafiDepartment of Chemistry, Universitas Gadjah Madaarticleantioxidantchemometricsfingerprintingftirs. polyanthumChemistryQD1-999ENIndonesian Journal of Chemistry, Vol 21, Iss 1, Pp 128-136 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	antioxidant chemometrics fingerprinting ftir s. polyanthum Chemistry QD1-999
spellingShingle	antioxidant chemometrics fingerprinting ftir s. polyanthum Chemistry QD1-999 Eti Rohaeti Fadila Karunina Mohamad Rafi FTIR-based Fingerprinting and Chemometrics for Rapid Investigation of Antioxidant Activity from <i>Syzygium polyanthum</i> Extracts
description	Syzygium polyanthum, known as salam in Indonesia, which is rich in phenolics compounds with high antioxidant activity. In this study, we performed the determination of total phenolics and characterization of the antioxidant activity of S. polyanthum leaves extracts using the FTIR-based fingerprinting technique. The extracts of S. polyanthum in water, ethanol, and ethanol-water (30, 50, and 70%) were measured for their antioxidant activity, total phenolics, and FTIR spectra. The antioxidant activity of S. polyanthum extract with different solvent extraction showed the highest antioxidant activity and total phenolic content is 70% and 50% ethanolic extract, respectively. The FTIR spectrum of each extract showed identical FTIR spectra patterns. According to their different solvent extraction, S. polyanthum extract could be grouped based on FTIR spectra using principal component analysis. Correlation between the functional group in the FTIR spectra with IC50 from S. polyanthum extract was analyzed using partial least square (PLS). The PLS analysis results showed that O–H, C–H sp3, C=O, C=C, C-O, and C–H aromatic are the main functional groups contributed to the antioxidant activity of S. polyanthum extract. FTIR-based fingerprinting combined with chemometrics could be used to classify different extracts of S. polyanthum and predicted functional groups having a significant contribution to antioxidant activity.
format	article
author	Eti Rohaeti Fadila Karunina Mohamad Rafi
author_facet	Eti Rohaeti Fadila Karunina Mohamad Rafi
author_sort	Eti Rohaeti
title	FTIR-based Fingerprinting and Chemometrics for Rapid Investigation of Antioxidant Activity from <i>Syzygium polyanthum</i> Extracts
title_short	FTIR-based Fingerprinting and Chemometrics for Rapid Investigation of Antioxidant Activity from <i>Syzygium polyanthum</i> Extracts
title_full	FTIR-based Fingerprinting and Chemometrics for Rapid Investigation of Antioxidant Activity from <i>Syzygium polyanthum</i> Extracts
title_fullStr	FTIR-based Fingerprinting and Chemometrics for Rapid Investigation of Antioxidant Activity from <i>Syzygium polyanthum</i> Extracts
title_full_unstemmed	FTIR-based Fingerprinting and Chemometrics for Rapid Investigation of Antioxidant Activity from <i>Syzygium polyanthum</i> Extracts
title_sort	ftir-based fingerprinting and chemometrics for rapid investigation of antioxidant activity from <i>syzygium polyanthum</i> extracts
publisher	Department of Chemistry, Universitas Gadjah Mada
publishDate	2020
url	https://doaj.org/article/0714007cd234453da079d3ef87e5657e
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FTIR-based Fingerprinting and Chemometrics for Rapid Investigation of Antioxidant Activity from <i>Syzygium polyanthum</i> Extracts

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