Influence of <i>TP53</i> Mutation on Survival of Diffuse Large B-Cell Lymphoma in the CAR T-Cell Era

Influence of <i>TP53</i> Mutation on Survival of Diffuse Large B-Cell Lymphoma in the CAR T-Cell Era

Refractory/relapsed diffuse large B-cell lymphoma (DLBCL) is associated with poor outcome. The clinical behavior and genetic landscape of DLBCL is heterogeneous and still not fully understood. <i>TP53</i> mutations in DLBCL have been identified as markers of poor prognosis and are often...

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Bibliographic Details
Main Authors: Edit Porpaczy, Philipp Wohlfarth, Oliver Königsbrügge, Werner Rabitsch, Cathrin Skrabs, Philipp Staber, Nina Worel, Leonhard Müllauer, Ingrid Simonitsch-Klupp, Christoph Kornauth, Johannes Rohrbeck, Ulrich Jaeger, Ana-Iris Schiefer
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
DLBCL
anti-CD19 CAR T cells
<i>TP53</i> mutation
<i>TP53</i> polymorphism
overall survival
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Online Access:https://doaj.org/article/0714d84a987446bcba6ed96dac848f51
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https://doaj.org/article/0714d84a987446bcba6ed96dac848f51

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