trans-Acting Factors and cis Elements Involved in the Human Inactive X Chromosome Organization and Compaction

During X chromosome inactivation, many chromatin changes occur on the future inactive X chromosome, including acquisition of a variety of repressive covalent histone modifications, heterochromatin protein associations, and DNA methylation of promoters. Here, we summarize trans-acting factors and cis...

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Autores principales: Zhuo Sun, Jinbo Fan, Yufeng Zhao
Formato: article
Lenguaje:EN
Publicado: Hindawi - Cambridge University Press 2021
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Acceso en línea:https://doaj.org/article/071b7af40ab64e5ba6f4578487539433
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spelling oai:doaj.org-article:071b7af40ab64e5ba6f45784875394332021-12-02T19:44:22Ztrans-Acting Factors and cis Elements Involved in the Human Inactive X Chromosome Organization and Compaction0016-67231469-507310.1155/2021/6683460https://doaj.org/article/071b7af40ab64e5ba6f45784875394332021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/6683460https://doaj.org/toc/0016-6723https://doaj.org/toc/1469-5073During X chromosome inactivation, many chromatin changes occur on the future inactive X chromosome, including acquisition of a variety of repressive covalent histone modifications, heterochromatin protein associations, and DNA methylation of promoters. Here, we summarize trans-acting factors and cis elements that have been shown to be involved in the human inactive X chromosome organization and compaction.Zhuo SunJinbo FanYufeng ZhaoHindawi - Cambridge University PressarticleGeneticsQH426-470ENGenetics Research, Vol 2021 (2021)
institution DOAJ
collection DOAJ
language EN
topic Genetics
QH426-470
spellingShingle Genetics
QH426-470
Zhuo Sun
Jinbo Fan
Yufeng Zhao
trans-Acting Factors and cis Elements Involved in the Human Inactive X Chromosome Organization and Compaction
description During X chromosome inactivation, many chromatin changes occur on the future inactive X chromosome, including acquisition of a variety of repressive covalent histone modifications, heterochromatin protein associations, and DNA methylation of promoters. Here, we summarize trans-acting factors and cis elements that have been shown to be involved in the human inactive X chromosome organization and compaction.
format article
author Zhuo Sun
Jinbo Fan
Yufeng Zhao
author_facet Zhuo Sun
Jinbo Fan
Yufeng Zhao
author_sort Zhuo Sun
title trans-Acting Factors and cis Elements Involved in the Human Inactive X Chromosome Organization and Compaction
title_short trans-Acting Factors and cis Elements Involved in the Human Inactive X Chromosome Organization and Compaction
title_full trans-Acting Factors and cis Elements Involved in the Human Inactive X Chromosome Organization and Compaction
title_fullStr trans-Acting Factors and cis Elements Involved in the Human Inactive X Chromosome Organization and Compaction
title_full_unstemmed trans-Acting Factors and cis Elements Involved in the Human Inactive X Chromosome Organization and Compaction
title_sort trans-acting factors and cis elements involved in the human inactive x chromosome organization and compaction
publisher Hindawi - Cambridge University Press
publishDate 2021
url https://doaj.org/article/071b7af40ab64e5ba6f4578487539433
work_keys_str_mv AT zhuosun transactingfactorsandciselementsinvolvedinthehumaninactivexchromosomeorganizationandcompaction
AT jinbofan transactingfactorsandciselementsinvolvedinthehumaninactivexchromosomeorganizationandcompaction
AT yufengzhao transactingfactorsandciselementsinvolvedinthehumaninactivexchromosomeorganizationandcompaction
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