Building Natural Product Libraries Using Quantitative Clade-Based and Chemical Clustering Strategies

Natural product drug discovery efforts rely on libraries of organisms to provide access to diverse pools of compounds. Actionable strategies to rationally maximize chemical diversity, rather than relying on serendipity, can add value to such efforts.

Guardado en:
Detalles Bibliográficos
Autores principales: Victoria M. Anderson, Karen L. Wendt, Fares Z. Najar, Laura-Isobel McCall, Robert H. Cichewicz
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://doaj.org/article/071bce9cdaf34b179c7452445a8e5e3f
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:071bce9cdaf34b179c7452445a8e5e3f
record_format dspace
spelling oai:doaj.org-article:071bce9cdaf34b179c7452445a8e5e3f2021-12-02T19:44:32ZBuilding Natural Product Libraries Using Quantitative Clade-Based and Chemical Clustering Strategies2379-507710.1128/mSystems.00644-21https://doaj.org/article/071bce9cdaf34b179c7452445a8e5e3f2021-10-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mSystems.00644-21https://doaj.org/toc/2379-5077 Natural product drug discovery efforts rely on libraries of organisms to provide access to diverse pools of compounds. Actionable strategies to rationally maximize chemical diversity, rather than relying on serendipity, can add value to such efforts.Victoria M. AndersonKaren L. WendtFares Z. NajarLaura-Isobel McCallRobert H. CichewiczAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmSystems, Vol 6, Iss 5 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Victoria M. Anderson
Karen L. Wendt
Fares Z. Najar
Laura-Isobel McCall
Robert H. Cichewicz
Building Natural Product Libraries Using Quantitative Clade-Based and Chemical Clustering Strategies
description Natural product drug discovery efforts rely on libraries of organisms to provide access to diverse pools of compounds. Actionable strategies to rationally maximize chemical diversity, rather than relying on serendipity, can add value to such efforts.
format article
author Victoria M. Anderson
Karen L. Wendt
Fares Z. Najar
Laura-Isobel McCall
Robert H. Cichewicz
author_facet Victoria M. Anderson
Karen L. Wendt
Fares Z. Najar
Laura-Isobel McCall
Robert H. Cichewicz
author_sort Victoria M. Anderson
title Building Natural Product Libraries Using Quantitative Clade-Based and Chemical Clustering Strategies
title_short Building Natural Product Libraries Using Quantitative Clade-Based and Chemical Clustering Strategies
title_full Building Natural Product Libraries Using Quantitative Clade-Based and Chemical Clustering Strategies
title_fullStr Building Natural Product Libraries Using Quantitative Clade-Based and Chemical Clustering Strategies
title_full_unstemmed Building Natural Product Libraries Using Quantitative Clade-Based and Chemical Clustering Strategies
title_sort building natural product libraries using quantitative clade-based and chemical clustering strategies
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/071bce9cdaf34b179c7452445a8e5e3f
work_keys_str_mv AT victoriamanderson buildingnaturalproductlibrariesusingquantitativecladebasedandchemicalclusteringstrategies
AT karenlwendt buildingnaturalproductlibrariesusingquantitativecladebasedandchemicalclusteringstrategies
AT faresznajar buildingnaturalproductlibrariesusingquantitativecladebasedandchemicalclusteringstrategies
AT lauraisobelmccall buildingnaturalproductlibrariesusingquantitativecladebasedandchemicalclusteringstrategies
AT roberthcichewicz buildingnaturalproductlibrariesusingquantitativecladebasedandchemicalclusteringstrategies
_version_ 1718376065707016192