Building Natural Product Libraries Using Quantitative Clade-Based and Chemical Clustering Strategies
Natural product drug discovery efforts rely on libraries of organisms to provide access to diverse pools of compounds. Actionable strategies to rationally maximize chemical diversity, rather than relying on serendipity, can add value to such efforts.
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American Society for Microbiology
2021
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oai:doaj.org-article:071bce9cdaf34b179c7452445a8e5e3f2021-12-02T19:44:32ZBuilding Natural Product Libraries Using Quantitative Clade-Based and Chemical Clustering Strategies2379-507710.1128/mSystems.00644-21https://doaj.org/article/071bce9cdaf34b179c7452445a8e5e3f2021-10-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mSystems.00644-21https://doaj.org/toc/2379-5077 Natural product drug discovery efforts rely on libraries of organisms to provide access to diverse pools of compounds. Actionable strategies to rationally maximize chemical diversity, rather than relying on serendipity, can add value to such efforts.Victoria M. AndersonKaren L. WendtFares Z. NajarLaura-Isobel McCallRobert H. CichewiczAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmSystems, Vol 6, Iss 5 (2021) |
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DOAJ |
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DOAJ |
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EN |
topic |
Microbiology QR1-502 |
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Microbiology QR1-502 Victoria M. Anderson Karen L. Wendt Fares Z. Najar Laura-Isobel McCall Robert H. Cichewicz Building Natural Product Libraries Using Quantitative Clade-Based and Chemical Clustering Strategies |
description |
Natural product drug discovery efforts rely on libraries of organisms to provide access to diverse pools of compounds. Actionable strategies to rationally maximize chemical diversity, rather than relying on serendipity, can add value to such efforts. |
format |
article |
author |
Victoria M. Anderson Karen L. Wendt Fares Z. Najar Laura-Isobel McCall Robert H. Cichewicz |
author_facet |
Victoria M. Anderson Karen L. Wendt Fares Z. Najar Laura-Isobel McCall Robert H. Cichewicz |
author_sort |
Victoria M. Anderson |
title |
Building Natural Product Libraries Using Quantitative Clade-Based and Chemical Clustering Strategies |
title_short |
Building Natural Product Libraries Using Quantitative Clade-Based and Chemical Clustering Strategies |
title_full |
Building Natural Product Libraries Using Quantitative Clade-Based and Chemical Clustering Strategies |
title_fullStr |
Building Natural Product Libraries Using Quantitative Clade-Based and Chemical Clustering Strategies |
title_full_unstemmed |
Building Natural Product Libraries Using Quantitative Clade-Based and Chemical Clustering Strategies |
title_sort |
building natural product libraries using quantitative clade-based and chemical clustering strategies |
publisher |
American Society for Microbiology |
publishDate |
2021 |
url |
https://doaj.org/article/071bce9cdaf34b179c7452445a8e5e3f |
work_keys_str_mv |
AT victoriamanderson buildingnaturalproductlibrariesusingquantitativecladebasedandchemicalclusteringstrategies AT karenlwendt buildingnaturalproductlibrariesusingquantitativecladebasedandchemicalclusteringstrategies AT faresznajar buildingnaturalproductlibrariesusingquantitativecladebasedandchemicalclusteringstrategies AT lauraisobelmccall buildingnaturalproductlibrariesusingquantitativecladebasedandchemicalclusteringstrategies AT roberthcichewicz buildingnaturalproductlibrariesusingquantitativecladebasedandchemicalclusteringstrategies |
_version_ |
1718376065707016192 |