Host genetic diversity drives variable central nervous system lesion distribution in chronic phase of Theiler's Murine Encephalomyelitis Virus (TMEV) infection.

Host genetic diversity drives variable central nervous system lesion distribution in chronic phase of Theiler's Murine Encephalomyelitis Virus (TMEV) infection.

Host genetic background is a significant driver of the variability in neurological responses to viral infection. Here, we leverage the genetically diverse Collaborative Cross (CC) mouse resource to better understand how chronic infection by Theiler's Murine Encephalomyelitis Virus (TMEV) elicit...

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Autores principales: Koedi S Lawley, Raquel R Rech, Faith Elenwa, Gang Han, Aracely A Perez Gomez, Katia Amstalden, C Jane Welsh, Colin R Young, David W Threadgill, Candice L Brinkmeyer-Langford
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/07223f1805384c1fae1ab5708c93dae4
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