Prevalence and Manifestation of Ototoxic Medications Among the Adult Attendees of The Audiovestibular unit at Al-Zahraa University Hospital, Cairo, Egypt

Background: Hearing loss is considered to be one of the most common factors of moderate to severe disability specially in the developing countries. Ototoxicity is inner ear damage due to usage of chemical substances, which can lead to either reversable or permanent hearing loss and/or vestibular los...

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Autores principales:	Iman Eladawy, Amal Ahmed, Samia Barghash, Hanaa Abu Elhassan
Formato:	article
Lenguaje:	EN
Publicado:	Al-Azhar University, Faculty of Medicine (Damietta) 2020
Materias:	ototoxicity hearing impairment tinnitus vertigo hearing screening Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/072aeeb8eb7548af934fad691db6b522
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spelling	oai:doaj.org-article:072aeeb8eb7548af934fad691db6b5222021-12-02T13:52:46ZPrevalence and Manifestation of Ototoxic Medications Among the Adult Attendees of The Audiovestibular unit at Al-Zahraa University Hospital, Cairo, Egypt2636-41742682-378010.21608/ijma.2020.33846.1140https://doaj.org/article/072aeeb8eb7548af934fad691db6b5222020-10-01T00:00:00Zhttps://ijma.journals.ekb.eg/article_104413_9abdd5d976d38ebafdc678a0f0162244.pdfhttps://doaj.org/toc/2636-4174https://doaj.org/toc/2682-3780Background: Hearing loss is considered to be one of the most common factors of moderate to severe disability specially in the developing countries. Ototoxicity is inner ear damage due to usage of chemical substances, which can lead to either reversable or permanent hearing loss and/or vestibular loss. Ototoxic hearing impairment can impact the quality of life by many ways; therefore, we should be very careful when it comes to choose drug therapy to minimize the risk. Aim of the work:To identify the commonly implicated ototoxic medications among the adult Egyptian population and to study its presenting features. Patients and Methods: This is a retrospective study, that involved review for the medical notes of all adult patients, who attended the Audio-Vestibular Unit with otological problems between January 2014 and December 2018. A total of 1110 medical folders were reviewed, and data were manually extracted. Results: The prevalence of ototoxic medication among the adult attendees was 26.6%. The most common manifestation was hearing impairment, as it was reported in 83.2% of the cases. Tinnitus came second by 70% followed by vertigo in 31%. Aspirin was the most common drug used [44.7%] of the patients, followed by aminoglycoside in 15% of our study sample, then the non-steroidal anti-inflammatory drugs (NSAIDS) in 14.3%. Conclusion: Audiometric screening is critical to capture the true prevalence of hearing loss. Baseline audiometric and vestibular function test should be performed before prescribing any ototoxic medication especially in patients with other associated risk factorsIman EladawyAmal AhmedSamia BarghashHanaa Abu ElhassanAl-Azhar University, Faculty of Medicine (Damietta)articleototoxicityhearing impairmenttinnitusvertigohearing screeningMedicine (General)R5-920ENInternational Journal of Medical Arts, Vol 2, Iss 4, Pp 722-729 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	ototoxicity hearing impairment tinnitus vertigo hearing screening Medicine (General) R5-920
spellingShingle	ototoxicity hearing impairment tinnitus vertigo hearing screening Medicine (General) R5-920 Iman Eladawy Amal Ahmed Samia Barghash Hanaa Abu Elhassan Prevalence and Manifestation of Ototoxic Medications Among the Adult Attendees of The Audiovestibular unit at Al-Zahraa University Hospital, Cairo, Egypt
description	Background: Hearing loss is considered to be one of the most common factors of moderate to severe disability specially in the developing countries. Ototoxicity is inner ear damage due to usage of chemical substances, which can lead to either reversable or permanent hearing loss and/or vestibular loss. Ototoxic hearing impairment can impact the quality of life by many ways; therefore, we should be very careful when it comes to choose drug therapy to minimize the risk. Aim of the work:To identify the commonly implicated ototoxic medications among the adult Egyptian population and to study its presenting features. Patients and Methods: This is a retrospective study, that involved review for the medical notes of all adult patients, who attended the Audio-Vestibular Unit with otological problems between January 2014 and December 2018. A total of 1110 medical folders were reviewed, and data were manually extracted. Results: The prevalence of ototoxic medication among the adult attendees was 26.6%. The most common manifestation was hearing impairment, as it was reported in 83.2% of the cases. Tinnitus came second by 70% followed by vertigo in 31%. Aspirin was the most common drug used [44.7%] of the patients, followed by aminoglycoside in 15% of our study sample, then the non-steroidal anti-inflammatory drugs (NSAIDS) in 14.3%. Conclusion: Audiometric screening is critical to capture the true prevalence of hearing loss. Baseline audiometric and vestibular function test should be performed before prescribing any ototoxic medication especially in patients with other associated risk factors
format	article
author	Iman Eladawy Amal Ahmed Samia Barghash Hanaa Abu Elhassan
author_facet	Iman Eladawy Amal Ahmed Samia Barghash Hanaa Abu Elhassan
author_sort	Iman Eladawy
title	Prevalence and Manifestation of Ototoxic Medications Among the Adult Attendees of The Audiovestibular unit at Al-Zahraa University Hospital, Cairo, Egypt
title_short	Prevalence and Manifestation of Ototoxic Medications Among the Adult Attendees of The Audiovestibular unit at Al-Zahraa University Hospital, Cairo, Egypt
title_full	Prevalence and Manifestation of Ototoxic Medications Among the Adult Attendees of The Audiovestibular unit at Al-Zahraa University Hospital, Cairo, Egypt
title_fullStr	Prevalence and Manifestation of Ototoxic Medications Among the Adult Attendees of The Audiovestibular unit at Al-Zahraa University Hospital, Cairo, Egypt
title_full_unstemmed	Prevalence and Manifestation of Ototoxic Medications Among the Adult Attendees of The Audiovestibular unit at Al-Zahraa University Hospital, Cairo, Egypt
title_sort	prevalence and manifestation of ototoxic medications among the adult attendees of the audiovestibular unit at al-zahraa university hospital, cairo, egypt
publisher	Al-Azhar University, Faculty of Medicine (Damietta)
publishDate	2020
url	https://doaj.org/article/072aeeb8eb7548af934fad691db6b522
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Prevalence and Manifestation of Ototoxic Medications Among the Adult Attendees of The Audiovestibular unit at Al-Zahraa University Hospital, Cairo, Egypt

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