Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19
The immune response is key in determining disease severity of COVID19. Here Nouailles et al., apply bulk proteomics and scRNA-Seq of lung and blood samples of SARS-CoV-2 infected Syrian hamsters and provide a temporal atlas of the systemic and pulmonary cellular responses.
Guardado en:
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2021
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/072ec28bf61e4f88ac379cb3aa53c111 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:072ec28bf61e4f88ac379cb3aa53c111 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:072ec28bf61e4f88ac379cb3aa53c1112021-12-02T18:50:59ZTemporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-1910.1038/s41467-021-25030-72041-1723https://doaj.org/article/072ec28bf61e4f88ac379cb3aa53c1112021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25030-7https://doaj.org/toc/2041-1723The immune response is key in determining disease severity of COVID19. Here Nouailles et al., apply bulk proteomics and scRNA-Seq of lung and blood samples of SARS-CoV-2 infected Syrian hamsters and provide a temporal atlas of the systemic and pulmonary cellular responses.Geraldine NouaillesEmanuel WylerPeter PennitzDylan PostmusDaria VladimirovaJulia KazmierskiFabian PottKristina DietertMichael MuellederVadim FarztdinovBenedikt ObermayerSandra-Maria WienholdSandro AndreottiThomas HoeflerBirgit SawitzkiChristian DrostenLeif E. SanderNorbert SuttorpMarkus RalserDieter BeuleAchim D. GruberChristine GoffinetMarkus LandthalerJakob TrimpertMartin WitzenrathNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-18 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Geraldine Nouailles Emanuel Wyler Peter Pennitz Dylan Postmus Daria Vladimirova Julia Kazmierski Fabian Pott Kristina Dietert Michael Muelleder Vadim Farztdinov Benedikt Obermayer Sandra-Maria Wienhold Sandro Andreotti Thomas Hoefler Birgit Sawitzki Christian Drosten Leif E. Sander Norbert Suttorp Markus Ralser Dieter Beule Achim D. Gruber Christine Goffinet Markus Landthaler Jakob Trimpert Martin Witzenrath Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19 |
| description |
The immune response is key in determining disease severity of COVID19. Here Nouailles et al., apply bulk proteomics and scRNA-Seq of lung and blood samples of SARS-CoV-2 infected Syrian hamsters and provide a temporal atlas of the systemic and pulmonary cellular responses. |
| format |
article |
| author |
Geraldine Nouailles Emanuel Wyler Peter Pennitz Dylan Postmus Daria Vladimirova Julia Kazmierski Fabian Pott Kristina Dietert Michael Muelleder Vadim Farztdinov Benedikt Obermayer Sandra-Maria Wienhold Sandro Andreotti Thomas Hoefler Birgit Sawitzki Christian Drosten Leif E. Sander Norbert Suttorp Markus Ralser Dieter Beule Achim D. Gruber Christine Goffinet Markus Landthaler Jakob Trimpert Martin Witzenrath |
| author_facet |
Geraldine Nouailles Emanuel Wyler Peter Pennitz Dylan Postmus Daria Vladimirova Julia Kazmierski Fabian Pott Kristina Dietert Michael Muelleder Vadim Farztdinov Benedikt Obermayer Sandra-Maria Wienhold Sandro Andreotti Thomas Hoefler Birgit Sawitzki Christian Drosten Leif E. Sander Norbert Suttorp Markus Ralser Dieter Beule Achim D. Gruber Christine Goffinet Markus Landthaler Jakob Trimpert Martin Witzenrath |
| author_sort |
Geraldine Nouailles |
| title |
Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19 |
| title_short |
Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19 |
| title_full |
Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19 |
| title_fullStr |
Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19 |
| title_full_unstemmed |
Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19 |
| title_sort |
temporal omics analysis in syrian hamsters unravel cellular effector responses to moderate covid-19 |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/072ec28bf61e4f88ac379cb3aa53c111 |
| work_keys_str_mv |
AT geraldinenouailles temporalomicsanalysisinsyrianhamstersunravelcellulareffectorresponsestomoderatecovid19 AT emanuelwyler temporalomicsanalysisinsyrianhamstersunravelcellulareffectorresponsestomoderatecovid19 AT peterpennitz temporalomicsanalysisinsyrianhamstersunravelcellulareffectorresponsestomoderatecovid19 AT dylanpostmus temporalomicsanalysisinsyrianhamstersunravelcellulareffectorresponsestomoderatecovid19 AT dariavladimirova temporalomicsanalysisinsyrianhamstersunravelcellulareffectorresponsestomoderatecovid19 AT juliakazmierski temporalomicsanalysisinsyrianhamstersunravelcellulareffectorresponsestomoderatecovid19 AT fabianpott temporalomicsanalysisinsyrianhamstersunravelcellulareffectorresponsestomoderatecovid19 AT kristinadietert temporalomicsanalysisinsyrianhamstersunravelcellulareffectorresponsestomoderatecovid19 AT michaelmuelleder temporalomicsanalysisinsyrianhamstersunravelcellulareffectorresponsestomoderatecovid19 AT vadimfarztdinov temporalomicsanalysisinsyrianhamstersunravelcellulareffectorresponsestomoderatecovid19 AT benediktobermayer temporalomicsanalysisinsyrianhamstersunravelcellulareffectorresponsestomoderatecovid19 AT sandramariawienhold temporalomicsanalysisinsyrianhamstersunravelcellulareffectorresponsestomoderatecovid19 AT sandroandreotti temporalomicsanalysisinsyrianhamstersunravelcellulareffectorresponsestomoderatecovid19 AT thomashoefler temporalomicsanalysisinsyrianhamstersunravelcellulareffectorresponsestomoderatecovid19 AT birgitsawitzki temporalomicsanalysisinsyrianhamstersunravelcellulareffectorresponsestomoderatecovid19 AT christiandrosten temporalomicsanalysisinsyrianhamstersunravelcellulareffectorresponsestomoderatecovid19 AT leifesander temporalomicsanalysisinsyrianhamstersunravelcellulareffectorresponsestomoderatecovid19 AT norbertsuttorp temporalomicsanalysisinsyrianhamstersunravelcellulareffectorresponsestomoderatecovid19 AT markusralser temporalomicsanalysisinsyrianhamstersunravelcellulareffectorresponsestomoderatecovid19 AT dieterbeule temporalomicsanalysisinsyrianhamstersunravelcellulareffectorresponsestomoderatecovid19 AT achimdgruber temporalomicsanalysisinsyrianhamstersunravelcellulareffectorresponsestomoderatecovid19 AT christinegoffinet temporalomicsanalysisinsyrianhamstersunravelcellulareffectorresponsestomoderatecovid19 AT markuslandthaler temporalomicsanalysisinsyrianhamstersunravelcellulareffectorresponsestomoderatecovid19 AT jakobtrimpert temporalomicsanalysisinsyrianhamstersunravelcellulareffectorresponsestomoderatecovid19 AT martinwitzenrath temporalomicsanalysisinsyrianhamstersunravelcellulareffectorresponsestomoderatecovid19 |
| _version_ |
1718377426471354368 |