Abandoning presumptive antimalarial treatment for febrile children aged less than five years--a case of running before we can walk?

<h4>Background to the debate</h4>Current guidelines recommend that all fever episodes in African children be treated presumptively with antimalarial drugs. But declining malarial transmission in parts of sub-Saharan Africa, declining proportions of fevers due to malaria, and the availabi...

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Autores principales:	Mike English, Hugh Reyburn, Catherine Goodman, Robert W Snow
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2009
Materias:	Medicine R
Acceso en línea:	https://doaj.org/article/07313dacf3b04873be5ba5537562cd6a
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spelling	oai:doaj.org-article:07313dacf3b04873be5ba5537562cd6a2021-11-25T05:37:23ZAbandoning presumptive antimalarial treatment for febrile children aged less than five years--a case of running before we can walk?1549-12771549-167610.1371/journal.pmed.1000015https://doaj.org/article/07313dacf3b04873be5ba5537562cd6a2009-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19127977/?tool=EBIhttps://doaj.org/toc/1549-1277https://doaj.org/toc/1549-1676<h4>Background to the debate</h4>Current guidelines recommend that all fever episodes in African children be treated presumptively with antimalarial drugs. But declining malarial transmission in parts of sub-Saharan Africa, declining proportions of fevers due to malaria, and the availability of rapid diagnostic tests mean it may be time for this policy to change. This debate examines whether enough evidence exists to support abandoning presumptive treatment and whether African health systems have the capacity to support a shift toward laboratory-confirmed rather than presumptive diagnosis and treatment of malaria in children under five.Mike EnglishHugh ReyburnCatherine GoodmanRobert W SnowPublic Library of Science (PLoS)articleMedicineRENPLoS Medicine, Vol 6, Iss 1, p e1000015 (2009)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R
spellingShingle	Medicine R Mike English Hugh Reyburn Catherine Goodman Robert W Snow Abandoning presumptive antimalarial treatment for febrile children aged less than five years--a case of running before we can walk?
description	<h4>Background to the debate</h4>Current guidelines recommend that all fever episodes in African children be treated presumptively with antimalarial drugs. But declining malarial transmission in parts of sub-Saharan Africa, declining proportions of fevers due to malaria, and the availability of rapid diagnostic tests mean it may be time for this policy to change. This debate examines whether enough evidence exists to support abandoning presumptive treatment and whether African health systems have the capacity to support a shift toward laboratory-confirmed rather than presumptive diagnosis and treatment of malaria in children under five.
format	article
author	Mike English Hugh Reyburn Catherine Goodman Robert W Snow
author_facet	Mike English Hugh Reyburn Catherine Goodman Robert W Snow
author_sort	Mike English
title	Abandoning presumptive antimalarial treatment for febrile children aged less than five years--a case of running before we can walk?
title_short	Abandoning presumptive antimalarial treatment for febrile children aged less than five years--a case of running before we can walk?
title_full	Abandoning presumptive antimalarial treatment for febrile children aged less than five years--a case of running before we can walk?
title_fullStr	Abandoning presumptive antimalarial treatment for febrile children aged less than five years--a case of running before we can walk?
title_full_unstemmed	Abandoning presumptive antimalarial treatment for febrile children aged less than five years--a case of running before we can walk?
title_sort	abandoning presumptive antimalarial treatment for febrile children aged less than five years--a case of running before we can walk?
publisher	Public Library of Science (PLoS)
publishDate	2009
url	https://doaj.org/article/07313dacf3b04873be5ba5537562cd6a
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Abandoning presumptive antimalarial treatment for febrile children aged less than five years--a case of running before we can walk?

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