LETR1 is a lymphatic endothelial-specific lncRNA governing cell proliferation and migration through KLF4 and SEMA3C

Long noncoding RNAs regulate tissue-specific gene expression. Here the authors profile lineage-specific lncRNAs in human dermal lymphatic and blood vascular endothelial cells (LECs and BECs) and show a role of LEC-specific lncRNA, LETR1, in cell proliferation and migration.

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Autores principales:	Luca Ducoli, Saumya Agrawal, Eliane Sibler, Tsukasa Kouno, Carlotta Tacconi, Chung-Chao Hon, Simone D. Berger, Daniela Müllhaupt, Yuliang He, Jihye Kim, Marco D’Addio, Lothar C. Dieterich, Piero Carninci, Michiel J. L. de Hoon, Jay W. Shin, Michael Detmar
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0736dd382c0449a084d82843bda88f5a
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spelling	oai:doaj.org-article:0736dd382c0449a084d82843bda88f5a2021-12-02T14:11:09ZLETR1 is a lymphatic endothelial-specific lncRNA governing cell proliferation and migration through KLF4 and SEMA3C10.1038/s41467-021-21217-02041-1723https://doaj.org/article/0736dd382c0449a084d82843bda88f5a2021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21217-0https://doaj.org/toc/2041-1723Long noncoding RNAs regulate tissue-specific gene expression. Here the authors profile lineage-specific lncRNAs in human dermal lymphatic and blood vascular endothelial cells (LECs and BECs) and show a role of LEC-specific lncRNA, LETR1, in cell proliferation and migration.Luca DucoliSaumya AgrawalEliane SiblerTsukasa KounoCarlotta TacconiChung-Chao HonSimone D. BergerDaniela MüllhauptYuliang HeJihye KimMarco D’AddioLothar C. DieterichPiero CarninciMichiel J. L. de HoonJay W. ShinMichael DetmarNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-22 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Luca Ducoli Saumya Agrawal Eliane Sibler Tsukasa Kouno Carlotta Tacconi Chung-Chao Hon Simone D. Berger Daniela Müllhaupt Yuliang He Jihye Kim Marco D’Addio Lothar C. Dieterich Piero Carninci Michiel J. L. de Hoon Jay W. Shin Michael Detmar LETR1 is a lymphatic endothelial-specific lncRNA governing cell proliferation and migration through KLF4 and SEMA3C
description	Long noncoding RNAs regulate tissue-specific gene expression. Here the authors profile lineage-specific lncRNAs in human dermal lymphatic and blood vascular endothelial cells (LECs and BECs) and show a role of LEC-specific lncRNA, LETR1, in cell proliferation and migration.
format	article
author	Luca Ducoli Saumya Agrawal Eliane Sibler Tsukasa Kouno Carlotta Tacconi Chung-Chao Hon Simone D. Berger Daniela Müllhaupt Yuliang He Jihye Kim Marco D’Addio Lothar C. Dieterich Piero Carninci Michiel J. L. de Hoon Jay W. Shin Michael Detmar
author_facet	Luca Ducoli Saumya Agrawal Eliane Sibler Tsukasa Kouno Carlotta Tacconi Chung-Chao Hon Simone D. Berger Daniela Müllhaupt Yuliang He Jihye Kim Marco D’Addio Lothar C. Dieterich Piero Carninci Michiel J. L. de Hoon Jay W. Shin Michael Detmar
author_sort	Luca Ducoli
title	LETR1 is a lymphatic endothelial-specific lncRNA governing cell proliferation and migration through KLF4 and SEMA3C
title_short	LETR1 is a lymphatic endothelial-specific lncRNA governing cell proliferation and migration through KLF4 and SEMA3C
title_full	LETR1 is a lymphatic endothelial-specific lncRNA governing cell proliferation and migration through KLF4 and SEMA3C
title_fullStr	LETR1 is a lymphatic endothelial-specific lncRNA governing cell proliferation and migration through KLF4 and SEMA3C
title_full_unstemmed	LETR1 is a lymphatic endothelial-specific lncRNA governing cell proliferation and migration through KLF4 and SEMA3C
title_sort	letr1 is a lymphatic endothelial-specific lncrna governing cell proliferation and migration through klf4 and sema3c
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/0736dd382c0449a084d82843bda88f5a
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LETR1 is a lymphatic endothelial-specific lncRNA governing cell proliferation and migration through KLF4 and SEMA3C

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