Study of the Physicochemical Properties and Anti-biofilm Effects of Synthesized Zinc Oxide Nanoparticles Using Artemisia Plant

Introduction: Recently, the biosynthesis of nanoparticles (NPs) using medicinal plants has attracted the attention of researchers due to their low cost and environmental compatibility. The aim of this study was to determine the anti-biofilm effects of zinc oxide (ZnO)-NPs synthesized using the Artem...

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Autores principales:	Sahar Galedari, Maryam Teimouri
Formato:	article
Lenguaje:	EN
Publicado:	Zabol University of Medical sciences 2020
Materias:	zno-nps artemisia pseudomonas aeruginosa anti-biofilm Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/0738e754482346b8aae477312c4a3698
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spelling	oai:doaj.org-article:0738e754482346b8aae477312c4a36982021-11-17T09:54:38ZStudy of the Physicochemical Properties and Anti-biofilm Effects of Synthesized Zinc Oxide Nanoparticles Using Artemisia Plant2476-664X10.34172/ijbsm.2020.18https://doaj.org/article/0738e754482346b8aae477312c4a36982020-09-01T00:00:00Zhttp://ijbsm.zbmu.ac.ir/PDF/ijbsm-20420https://doaj.org/toc/2476-664XIntroduction: Recently, the biosynthesis of nanoparticles (NPs) using medicinal plants has attracted the attention of researchers due to their low cost and environmental compatibility. The aim of this study was to determine the anti-biofilm effects of zinc oxide (ZnO)-NPs synthesized using the Artemisia plant extract on the clinical samples of Pseudomonas aeruginosa. Methods: In this experimental study, the alcoholic extract of Artemisia was prepared using the Soxhlet extraction method to synthesize ZnO-NPs. Then, the physical and chemical structures of the NPs were investigated using transmission electron microscopy (TEM), scanning electron microscopy (SEM), and ultraviolet/visible (UV-Vis) techniques. In addition, the gene expression of ndvB was analyzed by the polymerase chain reaction method. Finally, anti-biofilm and antimicrobial effects were evaluated using the minimum inhibitory concentration test and microtiter plate assay. Results: The antimicrobial results showed that ZnO-NPs had a spherical structure approved by the UV-Vis test. Further, ZnO-NPs had inhibitory effects on biofilm formation by P. aeruginosa strains. The results demonstrated that ZnO-NPs were effective on the isolations at the lowest and highest viscosities of 3.125 and 100 mg/mL, respectively. Conclusion: The biosynthesis of ZnO-NPs using the Artemisia plant extract is low cost and easy. Moreover, these NPs can be used as a drug with antimicrobial and anti-biofilm effects.Sahar GaledariMaryam TeimouriZabol University of Medical sciencesarticlezno-nps artemisia pseudomonas aeruginosa anti-biofilm Medicine (General)R5-920ENInternational Journal of Basic Science in Medicine, Vol 5, Iss 3, Pp 101-107 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	zno-nps artemisia pseudomonas aeruginosa anti-biofilm Medicine (General) R5-920
spellingShingle	zno-nps artemisia pseudomonas aeruginosa anti-biofilm Medicine (General) R5-920 Sahar Galedari Maryam Teimouri Study of the Physicochemical Properties and Anti-biofilm Effects of Synthesized Zinc Oxide Nanoparticles Using Artemisia Plant
description	Introduction: Recently, the biosynthesis of nanoparticles (NPs) using medicinal plants has attracted the attention of researchers due to their low cost and environmental compatibility. The aim of this study was to determine the anti-biofilm effects of zinc oxide (ZnO)-NPs synthesized using the Artemisia plant extract on the clinical samples of Pseudomonas aeruginosa. Methods: In this experimental study, the alcoholic extract of Artemisia was prepared using the Soxhlet extraction method to synthesize ZnO-NPs. Then, the physical and chemical structures of the NPs were investigated using transmission electron microscopy (TEM), scanning electron microscopy (SEM), and ultraviolet/visible (UV-Vis) techniques. In addition, the gene expression of ndvB was analyzed by the polymerase chain reaction method. Finally, anti-biofilm and antimicrobial effects were evaluated using the minimum inhibitory concentration test and microtiter plate assay. Results: The antimicrobial results showed that ZnO-NPs had a spherical structure approved by the UV-Vis test. Further, ZnO-NPs had inhibitory effects on biofilm formation by P. aeruginosa strains. The results demonstrated that ZnO-NPs were effective on the isolations at the lowest and highest viscosities of 3.125 and 100 mg/mL, respectively. Conclusion: The biosynthesis of ZnO-NPs using the Artemisia plant extract is low cost and easy. Moreover, these NPs can be used as a drug with antimicrobial and anti-biofilm effects.
format	article
author	Sahar Galedari Maryam Teimouri
author_facet	Sahar Galedari Maryam Teimouri
author_sort	Sahar Galedari
title	Study of the Physicochemical Properties and Anti-biofilm Effects of Synthesized Zinc Oxide Nanoparticles Using Artemisia Plant
title_short	Study of the Physicochemical Properties and Anti-biofilm Effects of Synthesized Zinc Oxide Nanoparticles Using Artemisia Plant
title_full	Study of the Physicochemical Properties and Anti-biofilm Effects of Synthesized Zinc Oxide Nanoparticles Using Artemisia Plant
title_fullStr	Study of the Physicochemical Properties and Anti-biofilm Effects of Synthesized Zinc Oxide Nanoparticles Using Artemisia Plant
title_full_unstemmed	Study of the Physicochemical Properties and Anti-biofilm Effects of Synthesized Zinc Oxide Nanoparticles Using Artemisia Plant
title_sort	study of the physicochemical properties and anti-biofilm effects of synthesized zinc oxide nanoparticles using artemisia plant
publisher	Zabol University of Medical sciences
publishDate	2020
url	https://doaj.org/article/0738e754482346b8aae477312c4a3698
work_keys_str_mv	AT sahargaledari studyofthephysicochemicalpropertiesandantibiofilmeffectsofsynthesizedzincoxidenanoparticlesusingartemisiaplant AT maryamteimouri studyofthephysicochemicalpropertiesandantibiofilmeffectsofsynthesizedzincoxidenanoparticlesusingartemisiaplant
_version_	1718425588320960512

Study of the Physicochemical Properties and Anti-biofilm Effects of Synthesized Zinc Oxide Nanoparticles Using Artemisia Plant

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