Coval: improving alignment quality and variant calling accuracy for next-generation sequencing data.

Coval: improving alignment quality and variant calling accuracy for next-generation sequencing data.

Accurate identification of DNA polymorphisms using next-generation sequencing technology is challenging because of a high rate of sequencing error and incorrect mapping of reads to reference genomes. Currently available short read aligners and DNA variant callers suffer from these problems. We devel...

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Autores principales: Shunichi Kosugi, Satoshi Natsume, Kentaro Yoshida, Daniel MacLean, Liliana Cano, Sophien Kamoun, Ryohei Terauchi
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/073e8266e16a424cbe5a7e604d0da610
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