Ultrasensitive antibody-aptamer plasmonic biosensor for malaria biomarker detection in whole blood

Reliable plasmonic biosensors with high throughput and ease of use are highly sought after. Here, the authors report a plasmon-enhanced fluorescence antibody-aptamer biosensor based on a gold nanoparticle array, and demonstrate its use for effective specific detection of a malaria marker, at femtomo...

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Autores principales: Antonio Minopoli, Bartolomeo Della Ventura, Bohdan Lenyk, Francesco Gentile, Julian A. Tanner, Andreas Offenhäusser, Dirk Mayer, Raffaele Velotta
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/07531cb4c8cc4d8bb8afabbfbe73a425
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Sumario:Reliable plasmonic biosensors with high throughput and ease of use are highly sought after. Here, the authors report a plasmon-enhanced fluorescence antibody-aptamer biosensor based on a gold nanoparticle array, and demonstrate its use for effective specific detection of a malaria marker, at femtomolar level, in whole blood.