Ultrasensitive antibody-aptamer plasmonic biosensor for malaria biomarker detection in whole blood

Reliable plasmonic biosensors with high throughput and ease of use are highly sought after. Here, the authors report a plasmon-enhanced fluorescence antibody-aptamer biosensor based on a gold nanoparticle array, and demonstrate its use for effective specific detection of a malaria marker, at femtomo...

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Autores principales: Antonio Minopoli, Bartolomeo Della Ventura, Bohdan Lenyk, Francesco Gentile, Julian A. Tanner, Andreas Offenhäusser, Dirk Mayer, Raffaele Velotta
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/07531cb4c8cc4d8bb8afabbfbe73a425
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spelling oai:doaj.org-article:07531cb4c8cc4d8bb8afabbfbe73a4252021-12-02T14:41:25ZUltrasensitive antibody-aptamer plasmonic biosensor for malaria biomarker detection in whole blood10.1038/s41467-020-19755-02041-1723https://doaj.org/article/07531cb4c8cc4d8bb8afabbfbe73a4252020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19755-0https://doaj.org/toc/2041-1723Reliable plasmonic biosensors with high throughput and ease of use are highly sought after. Here, the authors report a plasmon-enhanced fluorescence antibody-aptamer biosensor based on a gold nanoparticle array, and demonstrate its use for effective specific detection of a malaria marker, at femtomolar level, in whole blood.Antonio MinopoliBartolomeo Della VenturaBohdan LenykFrancesco GentileJulian A. TannerAndreas OffenhäusserDirk MayerRaffaele VelottaNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Antonio Minopoli
Bartolomeo Della Ventura
Bohdan Lenyk
Francesco Gentile
Julian A. Tanner
Andreas Offenhäusser
Dirk Mayer
Raffaele Velotta
Ultrasensitive antibody-aptamer plasmonic biosensor for malaria biomarker detection in whole blood
description Reliable plasmonic biosensors with high throughput and ease of use are highly sought after. Here, the authors report a plasmon-enhanced fluorescence antibody-aptamer biosensor based on a gold nanoparticle array, and demonstrate its use for effective specific detection of a malaria marker, at femtomolar level, in whole blood.
format article
author Antonio Minopoli
Bartolomeo Della Ventura
Bohdan Lenyk
Francesco Gentile
Julian A. Tanner
Andreas Offenhäusser
Dirk Mayer
Raffaele Velotta
author_facet Antonio Minopoli
Bartolomeo Della Ventura
Bohdan Lenyk
Francesco Gentile
Julian A. Tanner
Andreas Offenhäusser
Dirk Mayer
Raffaele Velotta
author_sort Antonio Minopoli
title Ultrasensitive antibody-aptamer plasmonic biosensor for malaria biomarker detection in whole blood
title_short Ultrasensitive antibody-aptamer plasmonic biosensor for malaria biomarker detection in whole blood
title_full Ultrasensitive antibody-aptamer plasmonic biosensor for malaria biomarker detection in whole blood
title_fullStr Ultrasensitive antibody-aptamer plasmonic biosensor for malaria biomarker detection in whole blood
title_full_unstemmed Ultrasensitive antibody-aptamer plasmonic biosensor for malaria biomarker detection in whole blood
title_sort ultrasensitive antibody-aptamer plasmonic biosensor for malaria biomarker detection in whole blood
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/07531cb4c8cc4d8bb8afabbfbe73a425
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