The morphopathological particuliarities of intrinsic innervation of the esophagus in newborns with esophageal atresia and inferior tracheoesophageal fistula
The authors present the results of a morphological study of the biological samples from patients treated with the inferior esophageal atresia with tracheoesophageal fistula, which included immunohistochemical examination of neuronal changes in the esophageal wall, predominantly in the anomalous segm...
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Group of Companies Med Expert, LLC, Kyev, Ukraine
2019
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oai:doaj.org-article:07592cec1e064643a25367ce9f27f1d12021-12-03T12:53:33ZThe morphopathological particuliarities of intrinsic innervation of the esophagus in newborns with esophageal atresia and inferior tracheoesophageal fistula2304-00412521-135810.15574/PS.2019.63.10https://doaj.org/article/07592cec1e064643a25367ce9f27f1d12019-06-01T00:00:00Zhttp://psu.med-expert.com.ua/article/view/181761https://doaj.org/toc/2304-0041https://doaj.org/toc/2521-1358The authors present the results of a morphological study of the biological samples from patients treated with the inferior esophageal atresia with tracheoesophageal fistula, which included immunohistochemical examination of neuronal changes in the esophageal wall, predominantly in the anomalous segment, with the need surgical involvement. The results obtained in the control group shows that the period of 36–37 weeks of gestation there is persisting glial cell component. The attested features are characteristic for the morpho-functional transition period from prematurity to maturity, being a specific neuronal cytology of the norm in the course of maturation of the child. Congenital morphopathological modifications of intramural ganglio-neural structures determined in both esophageal segments in cases of esophageal atresia with inferior tracheoesophageal fistula, concomitant with fibromuscular dysplasia, may be considered as factors with significant impact on esophageal motility regulation in children with esophageal atresia with tracheoesophageal fistula, and explains within certain limits their role in esophageal dismotility found postoperatively in this group of children.S. BabuciV. PetroviciS. GladunD. HaidarliA. PisarencoL. SiniținaD. DavidGroup of Companies Med Expert, LLC, Kyev, Ukrainearticleesophageal atresiatracheoesophageal fistulamorphologyimunohistochemieneuronal disordiesdismotilityPediatricsRJ1-570SurgeryRD1-811ENRUUKХірургія дитячого віку, Iss 2(63), Pp 10-17 (2019) |
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DOAJ |
| collection |
DOAJ |
| language |
EN RU UK |
| topic |
esophageal atresia tracheoesophageal fistula morphology imunohistochemie neuronal disordies dismotility Pediatrics RJ1-570 Surgery RD1-811 |
| spellingShingle |
esophageal atresia tracheoesophageal fistula morphology imunohistochemie neuronal disordies dismotility Pediatrics RJ1-570 Surgery RD1-811 S. Babuci V. Petrovici S. Gladun D. Haidarli A. Pisarenco L. Sinițina D. David The morphopathological particuliarities of intrinsic innervation of the esophagus in newborns with esophageal atresia and inferior tracheoesophageal fistula |
| description |
The authors present the results of a morphological study of the biological samples from patients treated with the inferior esophageal atresia with tracheoesophageal fistula, which included immunohistochemical examination of neuronal changes in the esophageal wall, predominantly in the anomalous segment, with the need surgical involvement. The results obtained in the control group shows that the period of 36–37 weeks of gestation there is persisting glial cell component. The attested features are characteristic for the morpho-functional transition period from prematurity to maturity, being a specific neuronal cytology of the norm in the course of maturation of the child. Congenital morphopathological modifications of intramural ganglio-neural structures determined in both esophageal segments in cases of esophageal atresia with inferior tracheoesophageal fistula, concomitant with fibromuscular dysplasia, may be considered as factors with significant impact on esophageal motility regulation in children with esophageal atresia with tracheoesophageal fistula, and explains within certain limits their role in esophageal dismotility found postoperatively in this group of children. |
| format |
article |
| author |
S. Babuci V. Petrovici S. Gladun D. Haidarli A. Pisarenco L. Sinițina D. David |
| author_facet |
S. Babuci V. Petrovici S. Gladun D. Haidarli A. Pisarenco L. Sinițina D. David |
| author_sort |
S. Babuci |
| title |
The morphopathological particuliarities of intrinsic innervation of the esophagus in newborns with esophageal atresia and inferior tracheoesophageal fistula |
| title_short |
The morphopathological particuliarities of intrinsic innervation of the esophagus in newborns with esophageal atresia and inferior tracheoesophageal fistula |
| title_full |
The morphopathological particuliarities of intrinsic innervation of the esophagus in newborns with esophageal atresia and inferior tracheoesophageal fistula |
| title_fullStr |
The morphopathological particuliarities of intrinsic innervation of the esophagus in newborns with esophageal atresia and inferior tracheoesophageal fistula |
| title_full_unstemmed |
The morphopathological particuliarities of intrinsic innervation of the esophagus in newborns with esophageal atresia and inferior tracheoesophageal fistula |
| title_sort |
morphopathological particuliarities of intrinsic innervation of the esophagus in newborns with esophageal atresia and inferior tracheoesophageal fistula |
| publisher |
Group of Companies Med Expert, LLC, Kyev, Ukraine |
| publishDate |
2019 |
| url |
https://doaj.org/article/07592cec1e064643a25367ce9f27f1d1 |
| work_keys_str_mv |
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