Single-molecule analysis of processive double-stranded RNA cleavage by Drosophila Dicer-2

Fly Dicer-2 is thought to use two distinct – processive or distributive – modes of cleavage by distinguishing the terminal structures of double-stranded RNA (dsRNA) substrates with the help of its cofactor LoquaciousPD (Loqs-PD). Here the authors show by single-molecule imaging that dsRNA terminal s...

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Autores principales: Masahiro Naganuma, Hisashi Tadakuma, Yukihide Tomari
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/075f930718904d9eb6b1018d79517ab4
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