A systematic review on the accuracy of diagnostic procedures for infravesical obstruction in boys.

<h4>Background</h4>Infravesical obstruction leads to kidney and bladder dysfunction in a significant proportion of boys. The aim of this review is to determine the value of diagnostic tests for ascertainment of infravesical obstruction in boys.<h4>Methodology</h4>We searched...

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Autores principales:	Pauline M L Hennus, Laetitia M O de Kort, J L H Bosch, Tom P V M de Jong, Geert J M G van der Heijden
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2014
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/0774552f287144a2997f192107763cf0
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spelling	oai:doaj.org-article:0774552f287144a2997f192107763cf02021-11-18T08:31:53ZA systematic review on the accuracy of diagnostic procedures for infravesical obstruction in boys.1932-620310.1371/journal.pone.0085474https://doaj.org/article/0774552f287144a2997f192107763cf02014-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24586242/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background</h4>Infravesical obstruction leads to kidney and bladder dysfunction in a significant proportion of boys. The aim of this review is to determine the value of diagnostic tests for ascertainment of infravesical obstruction in boys.<h4>Methodology</h4>We searched PubMed and EMBASE databases until January 1, 2013, to identify papers that described original diagnostic accuracy research for infravesical obstruction in boys. We extracted information on (1) patient characteristics and clinical presentation of PUV and (2) diagnostic pathway, (3) diagnostic accuracy measures and (4) assessed risk of bias.<h4>Principal findings</h4>We retrieved 15 studies describing various diagnostic pathways in 1,189 boys suspected for infravesical obstruction. The included studies reflect a broad clinical spectrum of patients, but all failed to present a standardised approach to confirm the presence and severity of obstruction. The risk of bias of included studies is rather high due to work-up bias and missing data.<h4>Conclusions</h4>As a consequence of low quality of methods of the available studies we put little confidence in the reported estimates for the diagnostic accuracy of US, VCUG and new additional tests for ruling in or ruling out infravesical obstruction. To date, firm evidence to support common diagnostic pathways is lacking. Hence, we are unable to draw conclusions on diagnostic accuracy of tests for infravesical obstruction. In order to be able to standardise the diagnostic pathway for infravesical obstruction, adequate design and transparent reporting is mandatory.Pauline M L HennusLaetitia M O de KortJ L H BoschTom P V M de JongGeert J M G van der HeijdenPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 9, Iss 2, p e85474 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Pauline M L Hennus Laetitia M O de Kort J L H Bosch Tom P V M de Jong Geert J M G van der Heijden A systematic review on the accuracy of diagnostic procedures for infravesical obstruction in boys.
description	<h4>Background</h4>Infravesical obstruction leads to kidney and bladder dysfunction in a significant proportion of boys. The aim of this review is to determine the value of diagnostic tests for ascertainment of infravesical obstruction in boys.<h4>Methodology</h4>We searched PubMed and EMBASE databases until January 1, 2013, to identify papers that described original diagnostic accuracy research for infravesical obstruction in boys. We extracted information on (1) patient characteristics and clinical presentation of PUV and (2) diagnostic pathway, (3) diagnostic accuracy measures and (4) assessed risk of bias.<h4>Principal findings</h4>We retrieved 15 studies describing various diagnostic pathways in 1,189 boys suspected for infravesical obstruction. The included studies reflect a broad clinical spectrum of patients, but all failed to present a standardised approach to confirm the presence and severity of obstruction. The risk of bias of included studies is rather high due to work-up bias and missing data.<h4>Conclusions</h4>As a consequence of low quality of methods of the available studies we put little confidence in the reported estimates for the diagnostic accuracy of US, VCUG and new additional tests for ruling in or ruling out infravesical obstruction. To date, firm evidence to support common diagnostic pathways is lacking. Hence, we are unable to draw conclusions on diagnostic accuracy of tests for infravesical obstruction. In order to be able to standardise the diagnostic pathway for infravesical obstruction, adequate design and transparent reporting is mandatory.
format	article
author	Pauline M L Hennus Laetitia M O de Kort J L H Bosch Tom P V M de Jong Geert J M G van der Heijden
author_facet	Pauline M L Hennus Laetitia M O de Kort J L H Bosch Tom P V M de Jong Geert J M G van der Heijden
author_sort	Pauline M L Hennus
title	A systematic review on the accuracy of diagnostic procedures for infravesical obstruction in boys.
title_short	A systematic review on the accuracy of diagnostic procedures for infravesical obstruction in boys.
title_full	A systematic review on the accuracy of diagnostic procedures for infravesical obstruction in boys.
title_fullStr	A systematic review on the accuracy of diagnostic procedures for infravesical obstruction in boys.
title_full_unstemmed	A systematic review on the accuracy of diagnostic procedures for infravesical obstruction in boys.
title_sort	systematic review on the accuracy of diagnostic procedures for infravesical obstruction in boys.
publisher	Public Library of Science (PLoS)
publishDate	2014
url	https://doaj.org/article/0774552f287144a2997f192107763cf0
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A systematic review on the accuracy of diagnostic procedures for infravesical obstruction in boys.

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