Histone variant H3F3A promotes lung cancer cell migration through intronic regulation

Histone variant H3F3A promotes lung cancer cell migration through intronic regulation

Histone variants act as transcriptional activators and repressors and have been linked to cancer progression. Park and Choi et al. show that the histone H3.3 overexpression is associated with early-stage lung cancer, and promotes cancer cell migration by upregulating a G-protein-coupled receptor.

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Autores principales: Seong-Min Park, Eun-Young Choi, Mingyun Bae, Sunshin Kim, Jong Bae Park, Heon Yoo, Jung Kyoon Choi, Youn-Jae Kim, Seung-Hoon Lee, In-Hoo Kim
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/07788f10331948db8924a111c4c9b877
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spelling oai:doaj.org-article:07788f10331948db8924a111c4c9b8772021-12-02T14:39:15ZHistone variant H3F3A promotes lung cancer cell migration through intronic regulation10.1038/ncomms129142041-1723https://doaj.org/article/07788f10331948db8924a111c4c9b8772016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms12914https://doaj.org/toc/2041-1723Histone variants act as transcriptional activators and repressors and have been linked to cancer progression. Park and Choi et al. show that the histone H3.3 overexpression is associated with early-stage lung cancer, and promotes cancer cell migration by upregulating a G-protein-coupled receptor.Seong-Min ParkEun-Young ChoiMingyun BaeSunshin KimJong Bae ParkHeon YooJung Kyoon ChoiYoun-Jae KimSeung-Hoon LeeIn-Hoo KimNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Seong-Min Park
Eun-Young Choi
Mingyun Bae
Sunshin Kim
Jong Bae Park
Heon Yoo
Jung Kyoon Choi
Youn-Jae Kim
Seung-Hoon Lee
In-Hoo Kim
Histone variant H3F3A promotes lung cancer cell migration through intronic regulation
description Histone variants act as transcriptional activators and repressors and have been linked to cancer progression. Park and Choi et al. show that the histone H3.3 overexpression is associated with early-stage lung cancer, and promotes cancer cell migration by upregulating a G-protein-coupled receptor.
format article
author Seong-Min Park
Eun-Young Choi
Mingyun Bae
Sunshin Kim
Jong Bae Park
Heon Yoo
Jung Kyoon Choi
Youn-Jae Kim
Seung-Hoon Lee
In-Hoo Kim
author_facet Seong-Min Park
Eun-Young Choi
Mingyun Bae
Sunshin Kim
Jong Bae Park
Heon Yoo
Jung Kyoon Choi
Youn-Jae Kim
Seung-Hoon Lee
In-Hoo Kim
author_sort Seong-Min Park
title Histone variant H3F3A promotes lung cancer cell migration through intronic regulation
title_short Histone variant H3F3A promotes lung cancer cell migration through intronic regulation
title_full Histone variant H3F3A promotes lung cancer cell migration through intronic regulation
title_fullStr Histone variant H3F3A promotes lung cancer cell migration through intronic regulation
title_full_unstemmed Histone variant H3F3A promotes lung cancer cell migration through intronic regulation
title_sort histone variant h3f3a promotes lung cancer cell migration through intronic regulation
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/07788f10331948db8924a111c4c9b877
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AT sunshinkim histonevarianth3f3apromoteslungcancercellmigrationthroughintronicregulation
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AT seunghoonlee histonevarianth3f3apromoteslungcancercellmigrationthroughintronicregulation
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