Histone variant H3F3A promotes lung cancer cell migration through intronic regulation

Código QR

Histone variant H3F3A promotes lung cancer cell migration through intronic regulation

Histone variants act as transcriptional activators and repressors and have been linked to cancer progression. Park and Choi et al. show that the histone H3.3 overexpression is associated with early-stage lung cancer, and promotes cancer cell migration by upregulating a G-protein-coupled receptor.

Guardado en:

Detalles Bibliográficos
Autores principales:	Seong-Min Park, Eun-Young Choi, Mingyun Bae, Sunshin Kim, Jong Bae Park, Heon Yoo, Jung Kyoon Choi, Youn-Jae Kim, Seung-Hoon Lee, In-Hoo Kim
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/07788f10331948db8924a111c4c9b877
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Photobiomodulation as an antioxidant substitute in post-thawing trauma of human stem cells from the apical papilla
por: Woori Choi, et al.
Publicado: (2021)

PGC-1α attenuates hydrogen peroxide-induced apoptotic cell death by upregulating Nrf-2 via GSK3β inactivation mediated by activated p38 in HK-2 Cells
por: Hoon-In Choi, et al.
Publicado: (2017)

NADPH oxidase 4 is required for the generation of macrophage migration inhibitory factor and host defense against Toxoplasma gondii infection
por: Ji Hye Kim, et al.
Publicado: (2017)

Anti-fibrotic effect of 6-bromo-indirubin-3′-oxime (6-BIO) via regulation of activator protein-1 (AP-1) and specificity protein-1 (SP-1) transcription factors in kidney cells
por: Jung Sun Park, et al.
Publicado: (2022)

Relationship between ion migration and interfacial degradation of CH3NH3PbI3 perovskite solar cells under thermal conditions
por: Seongtak Kim, et al.
Publicado: (2017)

ELF3 Is a Target That Promotes Therapeutic Efficiency in EGFR Tyrosine Kinase Inhibitor-Resistant Non-Small Cell Lung Cancer Cells via Inhibiting PKCί
por: Jeon-Soo Lee, et al.
Publicado: (2021)

Discovery of potential biomarkers in human melanoma cells with different metastatic potential by metabolic and lipidomic profiling
por: Hye-Youn Kim, et al.
Publicado: (2017)

Exploratory Profiling of Extracellular MicroRNAs in Cerebrospinal Fluid Comparing Leptomeningeal Metastasis with Other Central Nervous System Tumor Statuses
por: Ji Hye Im, et al.
Publicado: (2021)

The histone H3-lysine 4-methyltransferase Mll4 regulates the development of growth hormone-releasing hormone-producing neurons in the mouse hypothalamus
por: Christian Huisman, et al.
Publicado: (2021)

Milk Exosome-Derived MicroRNA-2478 Suppresses Melanogenesis through the Akt-GSK3β Pathway
por: In-Seon Bae, et al.
Publicado: (2021)

Macrophage migration inhibitory factor (MIF) inhibitor 4-IPP downregulates stemness phenotype and mesenchymal trans-differentiation after irradiation in glioblastoma multiforme.
por: Shin Heon Lee, et al.
Publicado: (2021)

The slope of cerebral oxyhemoglobin oscillation is associated with vascular reserve capacity in large artery steno-occlusion
por: Tae Jung Kim, et al.
Publicado: (2021)

Author Correction: The slope of cerebral oxyhemoglobin oscillation is associated with vascular reserve capacity in large artery steno-occlusion
por: Tae Jung Kim, et al.
Publicado: (2021)

A Pivotal Role for AP-1-Mediated Osteopontin Expression in the Increased Migration of Vascular Smooth Muscle Cells Stimulated With HMGB1
por: Eun Yeong Jeon, et al.
Publicado: (2021)

Genetic variants in histone modification regions are associated with the prognosis of lung adenocarcinoma
por: Hyo-Gyoung Kang, et al.
Publicado: (2021)

Cobalt–Iron–Phosphate Hydrogen Evolution Reaction Electrocatalyst for Solar-Driven Alkaline Seawater Electrolyzer
por: Chiho Kim, et al.
Publicado: (2021)

TLR4-mediated expression of Mac-1 in monocytes plays a pivotal role in monocyte adhesion to vascular endothelium.
por: Seung Jin Lee, et al.
Publicado: (2014)

Wnt-PLC-IP3-Connexin-Ca2+ axis maintains ependymal motile cilia in zebrafish spinal cord
por: Jun Zhang, et al.
Publicado: (2020)

FGF2-primed 3D spheroids producing IL-8 promote therapeutic angiogenesis in murine hindlimb ischemia
por: Jungkyun Choi, et al.
Publicado: (2021)

Nonsurgical treatment outcomes for surgical candidates with lumbar disc herniation: a comprehensive cohort study
por: Chi Heon Kim, et al.
Publicado: (2021)

Highly efficient, heat dissipating, stretchable organic light-emitting diodes based on a MoO3/Au/MoO3 electrode with encapsulation
por: Dae Keun Choi, et al.
Publicado: (2021)

Accuracy and precision of the spinal instability neoplastic score (SINS) for predicting vertebral compression fractures after radiotherapy in spinal metastases: a meta-analysis
por: Young Rak Kim, et al.
Publicado: (2021)

Highly stacked 3D organic integrated circuits with via-hole-less multilevel metal interconnects
por: Hocheon Yoo, et al.
Publicado: (2019)

The Ino80 complex mediates epigenetic centromere propagation via active removal of histone H3
por: Eun Shik Choi, et al.
Publicado: (2017)

Parental educational status independently predicts the risk of prevalent hypertension in young adults
por: Sang Heon Suh, et al.
Publicado: (2021)

Antibody targeting intracellular oncogenic Ras mutants exerts anti-tumour effects after systemic administration
por: Seung-Min Shin, et al.
Publicado: (2017)

High-spatial and colourimetric imaging of histone modifications in single senescent cells using plasmonic nanoprobes
por: Hyun Ji An, et al.
Publicado: (2021)

Triolein emulsion enhances temozolomide brain delivery: an experimental study in rats
por: Won-Bae Seung, et al.
Publicado: (2021)

Unaffected fellow eye neovascularization in patients with type 3 neovascularization: Incidence and risk factors.
por: Jae Hyuck Kwak, et al.
Publicado: (2021)

Quantitative analysis of retinal and choroidal microvascular changes in patients with diabetes
por: Mirinae Kim, et al.
Publicado: (2018)

Strong and ductile Fe-24Mn-3Cr alloy resistant against erosion-corrosion
por: Yeong Jae Jeong, et al.
Publicado: (2021)

High-Performance PVC Gel for Adaptive Micro-Lenses with Variable Focal Length
por: Jin Woo Bae, et al.
Publicado: (2017)

Anti-Obesity Effect of α-Cubebenol Isolated from <i>Schisandra chinensis</i> in 3T3-L1 Adipocytes
por: Su Jin Lee, et al.
Publicado: (2021)

Pigs Immunized with the Virus-like Particle Vaccine Are Protected against the Hepatitis E-3 Virus
por: Hyeon-Jeong Go, et al.
Publicado: (2021)

N-AS-triggered SPMs are direct regulators of microglia in a model of Alzheimer’s disease
por: Ju Youn Lee, et al.
Publicado: (2020)

Synchrotron X-ray induced acoustic imaging
por: Seongwook Choi, et al.
Publicado: (2021)

Reply to ‘Sulfisoxazole does not inhibit the secretion of small extracellular vesicles’
por: Chan-Hyeong Lee, et al.
Publicado: (2021)

Albumin inhibits the nuclear translocation of Smad3 via interleukin-1beta signaling in hepatic stellate cells
por: Ji Hoon Park, et al.
Publicado: (2021)

Differences in the gray-to-white matter ratio according to different computed tomography scanners for outcome prediction in post-cardiac arrest patients receiving target temperature management.
por: Jae Hun Oh, et al.
Publicado: (2021)

Propagating acoustic waves on a culture substrate regulate the directional collective cell migration
por: Chikahiro Imashiro, et al.
Publicado: (2021)