Conformation of methylated GGQ in the Peptidyl Transferase Center during Translation Termination

Abstract The universally conserved Gly-Gly-Gln (GGQ) tripeptide in release factors or release factor-like surveillance proteins is required to catalyze the release of nascent peptide in the ribosome. The glutamine of the GGQ is methylated post-translationally at the N5 position in vivo; this covalen...

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Autores principales: Fuxing Zeng, Hong Jin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/0779fdb0ae3b4c1fa8fd891756629555
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