Conformation of methylated GGQ in the Peptidyl Transferase Center during Translation Termination

Abstract The universally conserved Gly-Gly-Gln (GGQ) tripeptide in release factors or release factor-like surveillance proteins is required to catalyze the release of nascent peptide in the ribosome. The glutamine of the GGQ is methylated post-translationally at the N5 position in vivo; this covalen...

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Auteurs principaux: Fuxing Zeng, Hong Jin
Format: article
Langue:EN
Publié: Nature Portfolio 2018
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/0779fdb0ae3b4c1fa8fd891756629555
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