EFA6B regulates a stop signal for collective invasion in breast cancer

Reduced expression of EFA6B is found in highly metastatic breast cancer subtypes. Here, the authors report that loss of EFA6B promotes collective invasion through activation of the epithelial-to-mesenchymal transition program and CDC42-dependent signalling pathways in breast cancer.

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Autores principales:	Racha Fayad, Monserrat Vázquez Rojas, Mariagrazia Partisani, Pascal Finetti, Shiraz Dib, Sophie Abelanet, Virginie Virolle, Anne Farina, Olivier Cabaud, Marc Lopez, Daniel Birnbaum, François Bertucci, Michel Franco, Frédéric Luton
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0787bba0953b47b2823c7bc21ef9994c
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spelling	oai:doaj.org-article:0787bba0953b47b2823c7bc21ef9994c2021-12-02T15:51:01ZEFA6B regulates a stop signal for collective invasion in breast cancer10.1038/s41467-021-22522-42041-1723https://doaj.org/article/0787bba0953b47b2823c7bc21ef9994c2021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22522-4https://doaj.org/toc/2041-1723Reduced expression of EFA6B is found in highly metastatic breast cancer subtypes. Here, the authors report that loss of EFA6B promotes collective invasion through activation of the epithelial-to-mesenchymal transition program and CDC42-dependent signalling pathways in breast cancer.Racha FayadMonserrat Vázquez RojasMariagrazia PartisaniPascal FinettiShiraz DibSophie AbelanetVirginie VirolleAnne FarinaOlivier CabaudMarc LopezDaniel BirnbaumFrançois BertucciMichel FrancoFrédéric LutonNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Racha Fayad Monserrat Vázquez Rojas Mariagrazia Partisani Pascal Finetti Shiraz Dib Sophie Abelanet Virginie Virolle Anne Farina Olivier Cabaud Marc Lopez Daniel Birnbaum François Bertucci Michel Franco Frédéric Luton EFA6B regulates a stop signal for collective invasion in breast cancer
description	Reduced expression of EFA6B is found in highly metastatic breast cancer subtypes. Here, the authors report that loss of EFA6B promotes collective invasion through activation of the epithelial-to-mesenchymal transition program and CDC42-dependent signalling pathways in breast cancer.
format	article
author	Racha Fayad Monserrat Vázquez Rojas Mariagrazia Partisani Pascal Finetti Shiraz Dib Sophie Abelanet Virginie Virolle Anne Farina Olivier Cabaud Marc Lopez Daniel Birnbaum François Bertucci Michel Franco Frédéric Luton
author_facet	Racha Fayad Monserrat Vázquez Rojas Mariagrazia Partisani Pascal Finetti Shiraz Dib Sophie Abelanet Virginie Virolle Anne Farina Olivier Cabaud Marc Lopez Daniel Birnbaum François Bertucci Michel Franco Frédéric Luton
author_sort	Racha Fayad
title	EFA6B regulates a stop signal for collective invasion in breast cancer
title_short	EFA6B regulates a stop signal for collective invasion in breast cancer
title_full	EFA6B regulates a stop signal for collective invasion in breast cancer
title_fullStr	EFA6B regulates a stop signal for collective invasion in breast cancer
title_full_unstemmed	EFA6B regulates a stop signal for collective invasion in breast cancer
title_sort	efa6b regulates a stop signal for collective invasion in breast cancer
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/0787bba0953b47b2823c7bc21ef9994c
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EFA6B regulates a stop signal for collective invasion in breast cancer

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