EFA6B regulates a stop signal for collective invasion in breast cancer

EFA6B regulates a stop signal for collective invasion in breast cancer

Reduced expression of EFA6B is found in highly metastatic breast cancer subtypes. Here, the authors report that loss of EFA6B promotes collective invasion through activation of the epithelial-to-mesenchymal transition program and CDC42-dependent signalling pathways in breast cancer.

Saved in:
Bibliographic Details
Main Authors: Racha Fayad, Monserrat Vázquez Rojas, Mariagrazia Partisani, Pascal Finetti, Shiraz Dib, Sophie Abelanet, Virginie Virolle, Anne Farina, Olivier Cabaud, Marc Lopez, Daniel Birnbaum, François Bertucci, Michel Franco, Frédéric Luton
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Science
Q
Online Access:https://doaj.org/article/0787bba0953b47b2823c7bc21ef9994c
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/0787bba0953b47b2823c7bc21ef9994c

Similar Items