HIV-associated gut dysbiosis is independent of sexual practice and correlates with noncommunicable diseases

HIV-associated gut dysbiosis is independent of sexual practice and correlates with noncommunicable diseases

The role of sexual practice in HIV-associated gut microbiota remains poorly understood. Here, in a cohort of chronically treated HIV-infected people, the authors show microbiome signatures to be independent of sex and sexual practice and that the extent of dysbiosis correlates with nadir CD4, inflam...

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Auteurs principaux: I. Vujkovic-Cvijin, O. Sortino, E. Verheij, J. Sklar, F. W. Wit, N. A. Kootstra, B. Sellers, J. M. Brenchley, J. Ananworanich, M. Schim van der Loeff, Y. Belkaid, P. Reiss, I. Sereti
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Science
Q
Accès en ligne:https://doaj.org/article/078814d98ea64316b04836c17cec0280
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Résumé:The role of sexual practice in HIV-associated gut microbiota remains poorly understood. Here, in a cohort of chronically treated HIV-infected people, the authors show microbiome signatures to be independent of sex and sexual practice and that the extent of dysbiosis correlates with nadir CD4, inflammatory markers, and comorbidities.

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