Correlation between Vitamin-D Level and Pulmonary Function Tests in Children with Bronchial Asthma

Background: Bronchial asthma Affecting 1-18% of children in different countries, it widely distributed chronic respiratory disease. vitamin-D increase calcium absorption from the gastrointestinal tract, determines bone health and regulates neuromuscular function. In addition, vitamin-D is a potent i...

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Autores principales:	Magdy Sakr, Mohamed Elsamnody, Atef Elrifai, Hesham Abd-Al-Samee, Ahmed Saad
Formato:	article
Lenguaje:	EN
Publicado:	Al-Azhar University, Faculty of Medicine (Damietta) 2020
Materias:	bronchial asthma children lung function vitamin-d correlation Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/078d28104833439ba8772d73625b471a
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spelling	oai:doaj.org-article:078d28104833439ba8772d73625b471a2021-12-02T10:38:27ZCorrelation between Vitamin-D Level and Pulmonary Function Tests in Children with Bronchial Asthma2636-41742682-378010.21608/ijma.2020.14621.1018https://doaj.org/article/078d28104833439ba8772d73625b471a2020-01-01T00:00:00Zhttps://ijma.journals.ekb.eg/article_69864_615d550e96fdf7ceccbe21730189e357.pdfhttps://doaj.org/toc/2636-4174https://doaj.org/toc/2682-3780Background: Bronchial asthma Affecting 1-18% of children in different countries, it widely distributed chronic respiratory disease. vitamin-D increase calcium absorption from the gastrointestinal tract, determines bone health and regulates neuromuscular function. In addition, vitamin-D is a potent immune system regulator, and it has a potential role in various allergic diseases. Aim of the work: To estimate the association between asthma and Vitamin-D in pediatrics. Patients and methods: The present work is a case control study included 150 (100 asthmatic children and 50 healthy control) children aged between 5 and 12 years. Serum 25- hydroxy vitamin-D levels were evaluated and compared between two groups. Association between vitamin-D and pulmonary function was studied in asthmatic children. Results: Cases had significantly lower values of FEV1%, FEV1/FVC ratio and vitamin-D levels when compared to controls (53.20±6.27, 68.64±4.42, 24.44±20.92 vs 126.44±10.15, 107.20±5.05 and 84.25±41.79 successively). In addition, vitamin-D was positively and significantly correlated with pulmonary function tests (FEV1% and FEV1/FVC ratio). Conclusion: Children with bronchial asthma suffered from marked reduction of vitamin-D which correlated with asthma severity.Magdy SakrMohamed ElsamnodyAtef ElrifaiHesham Abd-Al-SameeAhmed SaadAl-Azhar University, Faculty of Medicine (Damietta)articlebronchial asthmachildrenlung functionvitamin-dcorrelationMedicine (General)R5-920ENInternational Journal of Medical Arts, Vol 2, Iss 1, Pp 308-312 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	bronchial asthma children lung function vitamin-d correlation Medicine (General) R5-920
spellingShingle	bronchial asthma children lung function vitamin-d correlation Medicine (General) R5-920 Magdy Sakr Mohamed Elsamnody Atef Elrifai Hesham Abd-Al-Samee Ahmed Saad Correlation between Vitamin-D Level and Pulmonary Function Tests in Children with Bronchial Asthma
description	Background: Bronchial asthma Affecting 1-18% of children in different countries, it widely distributed chronic respiratory disease. vitamin-D increase calcium absorption from the gastrointestinal tract, determines bone health and regulates neuromuscular function. In addition, vitamin-D is a potent immune system regulator, and it has a potential role in various allergic diseases. Aim of the work: To estimate the association between asthma and Vitamin-D in pediatrics. Patients and methods: The present work is a case control study included 150 (100 asthmatic children and 50 healthy control) children aged between 5 and 12 years. Serum 25- hydroxy vitamin-D levels were evaluated and compared between two groups. Association between vitamin-D and pulmonary function was studied in asthmatic children. Results: Cases had significantly lower values of FEV1%, FEV1/FVC ratio and vitamin-D levels when compared to controls (53.20±6.27, 68.64±4.42, 24.44±20.92 vs 126.44±10.15, 107.20±5.05 and 84.25±41.79 successively). In addition, vitamin-D was positively and significantly correlated with pulmonary function tests (FEV1% and FEV1/FVC ratio). Conclusion: Children with bronchial asthma suffered from marked reduction of vitamin-D which correlated with asthma severity.
format	article
author	Magdy Sakr Mohamed Elsamnody Atef Elrifai Hesham Abd-Al-Samee Ahmed Saad
author_facet	Magdy Sakr Mohamed Elsamnody Atef Elrifai Hesham Abd-Al-Samee Ahmed Saad
author_sort	Magdy Sakr
title	Correlation between Vitamin-D Level and Pulmonary Function Tests in Children with Bronchial Asthma
title_short	Correlation between Vitamin-D Level and Pulmonary Function Tests in Children with Bronchial Asthma
title_full	Correlation between Vitamin-D Level and Pulmonary Function Tests in Children with Bronchial Asthma
title_fullStr	Correlation between Vitamin-D Level and Pulmonary Function Tests in Children with Bronchial Asthma
title_full_unstemmed	Correlation between Vitamin-D Level and Pulmonary Function Tests in Children with Bronchial Asthma
title_sort	correlation between vitamin-d level and pulmonary function tests in children with bronchial asthma
publisher	Al-Azhar University, Faculty of Medicine (Damietta)
publishDate	2020
url	https://doaj.org/article/078d28104833439ba8772d73625b471a
work_keys_str_mv	AT magdysakr correlationbetweenvitamindlevelandpulmonaryfunctiontestsinchildrenwithbronchialasthma AT mohamedelsamnody correlationbetweenvitamindlevelandpulmonaryfunctiontestsinchildrenwithbronchialasthma AT atefelrifai correlationbetweenvitamindlevelandpulmonaryfunctiontestsinchildrenwithbronchialasthma AT heshamabdalsamee correlationbetweenvitamindlevelandpulmonaryfunctiontestsinchildrenwithbronchialasthma AT ahmedsaad correlationbetweenvitamindlevelandpulmonaryfunctiontestsinchildrenwithbronchialasthma
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Correlation between Vitamin-D Level and Pulmonary Function Tests in Children with Bronchial Asthma

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