Telomere-mediated chromosomal instability triggers TLR4 induced inflammation and death in mice.
<h4>Background</h4>Telomeres are essential to maintain chromosomal stability. Cells derived from mice lacking telomerase RNA component (mTERC-/- mice) display elevated telomere-mediated chromosome instability. Age-dependent telomere shortening and associated chromosome instability reduce...
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Main Authors: | , , , |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2010
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Subjects: | |
Online Access: | https://doaj.org/article/0794f14187fb4e1eb68322c29a38ff9d |
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