Coordination of two enhancers drives expression of olfactory trace amine-associated receptors

In our nose, some neuron subpopulations express a family of trace amine associated receptors (TAARs, smelling e.g., rotten fish). Fei et al. identify two conserved enhancers across placental mammals named TAAR enhancer 1 and 2 that coordinately regulate expression of the entire Taar gene repertoire.

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Bibliographic Details
Main Authors:	Aimei Fei, Wanqing Wu, Longzhi Tan, Cheng Tang, Zhengrong Xu, Xiaona Huo, Hongqiang Bao, Yalei Kong, Mark Johnson, Griffin Hartmann, Mustafa Talay, Cheng Yang, Clemens Riegler, Kristian J. Herrera, Florian Engert, X. Sunney Xie, Gilad Barnea, Stephen D. Liberles, Hui Yang, Qian Li
Format:	article
Language:	EN
Published:	Nature Portfolio 2021
Subjects:	Science Q
Online Access:	https://doaj.org/article/07963a2e4a2d4564b3ecbf903cb100b4
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Summary:	In our nose, some neuron subpopulations express a family of trace amine associated receptors (TAARs, smelling e.g., rotten fish). Fei et al. identify two conserved enhancers across placental mammals named TAAR enhancer 1 and 2 that coordinately regulate expression of the entire Taar gene repertoire.

Coordination of two enhancers drives expression of olfactory trace amine-associated receptors

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