Coordination of two enhancers drives expression of olfactory trace amine-associated receptors

In our nose, some neuron subpopulations express a family of trace amine associated receptors (TAARs, smelling e.g., rotten fish). Fei et al. identify two conserved enhancers across placental mammals named TAAR enhancer 1 and 2 that coordinately regulate expression of the entire Taar gene repertoire.

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Autores principales: Aimei Fei, Wanqing Wu, Longzhi Tan, Cheng Tang, Zhengrong Xu, Xiaona Huo, Hongqiang Bao, Yalei Kong, Mark Johnson, Griffin Hartmann, Mustafa Talay, Cheng Yang, Clemens Riegler, Kristian J. Herrera, Florian Engert, X. Sunney Xie, Gilad Barnea, Stephen D. Liberles, Hui Yang, Qian Li
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/07963a2e4a2d4564b3ecbf903cb100b4
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spelling oai:doaj.org-article:07963a2e4a2d4564b3ecbf903cb100b42021-12-02T16:04:21ZCoordination of two enhancers drives expression of olfactory trace amine-associated receptors10.1038/s41467-021-23823-42041-1723https://doaj.org/article/07963a2e4a2d4564b3ecbf903cb100b42021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23823-4https://doaj.org/toc/2041-1723In our nose, some neuron subpopulations express a family of trace amine associated receptors (TAARs, smelling e.g., rotten fish). Fei et al. identify two conserved enhancers across placental mammals named TAAR enhancer 1 and 2 that coordinately regulate expression of the entire Taar gene repertoire.Aimei FeiWanqing WuLongzhi TanCheng TangZhengrong XuXiaona HuoHongqiang BaoYalei KongMark JohnsonGriffin HartmannMustafa TalayCheng YangClemens RieglerKristian J. HerreraFlorian EngertX. Sunney XieGilad BarneaStephen D. LiberlesHui YangQian LiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Aimei Fei
Wanqing Wu
Longzhi Tan
Cheng Tang
Zhengrong Xu
Xiaona Huo
Hongqiang Bao
Yalei Kong
Mark Johnson
Griffin Hartmann
Mustafa Talay
Cheng Yang
Clemens Riegler
Kristian J. Herrera
Florian Engert
X. Sunney Xie
Gilad Barnea
Stephen D. Liberles
Hui Yang
Qian Li
Coordination of two enhancers drives expression of olfactory trace amine-associated receptors
description In our nose, some neuron subpopulations express a family of trace amine associated receptors (TAARs, smelling e.g., rotten fish). Fei et al. identify two conserved enhancers across placental mammals named TAAR enhancer 1 and 2 that coordinately regulate expression of the entire Taar gene repertoire.
format article
author Aimei Fei
Wanqing Wu
Longzhi Tan
Cheng Tang
Zhengrong Xu
Xiaona Huo
Hongqiang Bao
Yalei Kong
Mark Johnson
Griffin Hartmann
Mustafa Talay
Cheng Yang
Clemens Riegler
Kristian J. Herrera
Florian Engert
X. Sunney Xie
Gilad Barnea
Stephen D. Liberles
Hui Yang
Qian Li
author_facet Aimei Fei
Wanqing Wu
Longzhi Tan
Cheng Tang
Zhengrong Xu
Xiaona Huo
Hongqiang Bao
Yalei Kong
Mark Johnson
Griffin Hartmann
Mustafa Talay
Cheng Yang
Clemens Riegler
Kristian J. Herrera
Florian Engert
X. Sunney Xie
Gilad Barnea
Stephen D. Liberles
Hui Yang
Qian Li
author_sort Aimei Fei
title Coordination of two enhancers drives expression of olfactory trace amine-associated receptors
title_short Coordination of two enhancers drives expression of olfactory trace amine-associated receptors
title_full Coordination of two enhancers drives expression of olfactory trace amine-associated receptors
title_fullStr Coordination of two enhancers drives expression of olfactory trace amine-associated receptors
title_full_unstemmed Coordination of two enhancers drives expression of olfactory trace amine-associated receptors
title_sort coordination of two enhancers drives expression of olfactory trace amine-associated receptors
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/07963a2e4a2d4564b3ecbf903cb100b4
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