Coordination of two enhancers drives expression of olfactory trace amine-associated receptors
In our nose, some neuron subpopulations express a family of trace amine associated receptors (TAARs, smelling e.g., rotten fish). Fei et al. identify two conserved enhancers across placental mammals named TAAR enhancer 1 and 2 that coordinately regulate expression of the entire Taar gene repertoire.
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Nature Portfolio
2021
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oai:doaj.org-article:07963a2e4a2d4564b3ecbf903cb100b42021-12-02T16:04:21ZCoordination of two enhancers drives expression of olfactory trace amine-associated receptors10.1038/s41467-021-23823-42041-1723https://doaj.org/article/07963a2e4a2d4564b3ecbf903cb100b42021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23823-4https://doaj.org/toc/2041-1723In our nose, some neuron subpopulations express a family of trace amine associated receptors (TAARs, smelling e.g., rotten fish). Fei et al. identify two conserved enhancers across placental mammals named TAAR enhancer 1 and 2 that coordinately regulate expression of the entire Taar gene repertoire.Aimei FeiWanqing WuLongzhi TanCheng TangZhengrong XuXiaona HuoHongqiang BaoYalei KongMark JohnsonGriffin HartmannMustafa TalayCheng YangClemens RieglerKristian J. HerreraFlorian EngertX. Sunney XieGilad BarneaStephen D. LiberlesHui YangQian LiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-19 (2021) |
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Science Q Aimei Fei Wanqing Wu Longzhi Tan Cheng Tang Zhengrong Xu Xiaona Huo Hongqiang Bao Yalei Kong Mark Johnson Griffin Hartmann Mustafa Talay Cheng Yang Clemens Riegler Kristian J. Herrera Florian Engert X. Sunney Xie Gilad Barnea Stephen D. Liberles Hui Yang Qian Li Coordination of two enhancers drives expression of olfactory trace amine-associated receptors |
description |
In our nose, some neuron subpopulations express a family of trace amine associated receptors (TAARs, smelling e.g., rotten fish). Fei et al. identify two conserved enhancers across placental mammals named TAAR enhancer 1 and 2 that coordinately regulate expression of the entire Taar gene repertoire. |
format |
article |
author |
Aimei Fei Wanqing Wu Longzhi Tan Cheng Tang Zhengrong Xu Xiaona Huo Hongqiang Bao Yalei Kong Mark Johnson Griffin Hartmann Mustafa Talay Cheng Yang Clemens Riegler Kristian J. Herrera Florian Engert X. Sunney Xie Gilad Barnea Stephen D. Liberles Hui Yang Qian Li |
author_facet |
Aimei Fei Wanqing Wu Longzhi Tan Cheng Tang Zhengrong Xu Xiaona Huo Hongqiang Bao Yalei Kong Mark Johnson Griffin Hartmann Mustafa Talay Cheng Yang Clemens Riegler Kristian J. Herrera Florian Engert X. Sunney Xie Gilad Barnea Stephen D. Liberles Hui Yang Qian Li |
author_sort |
Aimei Fei |
title |
Coordination of two enhancers drives expression of olfactory trace amine-associated receptors |
title_short |
Coordination of two enhancers drives expression of olfactory trace amine-associated receptors |
title_full |
Coordination of two enhancers drives expression of olfactory trace amine-associated receptors |
title_fullStr |
Coordination of two enhancers drives expression of olfactory trace amine-associated receptors |
title_full_unstemmed |
Coordination of two enhancers drives expression of olfactory trace amine-associated receptors |
title_sort |
coordination of two enhancers drives expression of olfactory trace amine-associated receptors |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/07963a2e4a2d4564b3ecbf903cb100b4 |
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