Intrauterine Zika virus infection of pregnant immunocompetent mice models transplacental transmission and adverse perinatal outcomes

Zika virus infection of pregnant women is associated with congenital neurological disorders. Here, Vermillionet al. develop an immunocompetent mouse model for identification of factors at the maternal-fetal interface that contribute to adverse perinatal outcomes.

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Autores principales: Meghan S. Vermillion, Jun Lei, Yahya Shabi, Victoria K. Baxter, Nathan P. Crilly, Michael McLane, Diane E. Griffin, Andrew Pekosz, Sabra L. Klein, Irina Burd
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/07a4afde47914fd08d15bf3ae8f56bc7
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spelling oai:doaj.org-article:07a4afde47914fd08d15bf3ae8f56bc72021-12-02T14:42:35ZIntrauterine Zika virus infection of pregnant immunocompetent mice models transplacental transmission and adverse perinatal outcomes10.1038/ncomms145752041-1723https://doaj.org/article/07a4afde47914fd08d15bf3ae8f56bc72017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14575https://doaj.org/toc/2041-1723Zika virus infection of pregnant women is associated with congenital neurological disorders. Here, Vermillionet al. develop an immunocompetent mouse model for identification of factors at the maternal-fetal interface that contribute to adverse perinatal outcomes.Meghan S. VermillionJun LeiYahya ShabiVictoria K. BaxterNathan P. CrillyMichael McLaneDiane E. GriffinAndrew PekoszSabra L. KleinIrina BurdNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Meghan S. Vermillion
Jun Lei
Yahya Shabi
Victoria K. Baxter
Nathan P. Crilly
Michael McLane
Diane E. Griffin
Andrew Pekosz
Sabra L. Klein
Irina Burd
Intrauterine Zika virus infection of pregnant immunocompetent mice models transplacental transmission and adverse perinatal outcomes
description Zika virus infection of pregnant women is associated with congenital neurological disorders. Here, Vermillionet al. develop an immunocompetent mouse model for identification of factors at the maternal-fetal interface that contribute to adverse perinatal outcomes.
format article
author Meghan S. Vermillion
Jun Lei
Yahya Shabi
Victoria K. Baxter
Nathan P. Crilly
Michael McLane
Diane E. Griffin
Andrew Pekosz
Sabra L. Klein
Irina Burd
author_facet Meghan S. Vermillion
Jun Lei
Yahya Shabi
Victoria K. Baxter
Nathan P. Crilly
Michael McLane
Diane E. Griffin
Andrew Pekosz
Sabra L. Klein
Irina Burd
author_sort Meghan S. Vermillion
title Intrauterine Zika virus infection of pregnant immunocompetent mice models transplacental transmission and adverse perinatal outcomes
title_short Intrauterine Zika virus infection of pregnant immunocompetent mice models transplacental transmission and adverse perinatal outcomes
title_full Intrauterine Zika virus infection of pregnant immunocompetent mice models transplacental transmission and adverse perinatal outcomes
title_fullStr Intrauterine Zika virus infection of pregnant immunocompetent mice models transplacental transmission and adverse perinatal outcomes
title_full_unstemmed Intrauterine Zika virus infection of pregnant immunocompetent mice models transplacental transmission and adverse perinatal outcomes
title_sort intrauterine zika virus infection of pregnant immunocompetent mice models transplacental transmission and adverse perinatal outcomes
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/07a4afde47914fd08d15bf3ae8f56bc7
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