Prevalence of type 2 diabetes mellitus and other abnormalities of carbohydrate metabolism depending on diagnostic criteria

Aim. To assess current criteria for type 2 diabetes mellitus. Materials and methods. This screening study involving 2,368 residents of two municipal districts of the Moscow region was designed to elucidate differencesin the prevalence of abnormalities of carbohydrate metabolism depending on diagno...

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Autores principales: Alexander Vasil'evich Dreval', Inna Vladimirovna Misnikova, Il'ya Alexeevich Barsukov, Galina Vladimirovna Ponchakova, Anatoliy Vasil'evich Kuznetsov
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RU
Publicado: Endocrinology Research Centre 2010
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Acceso en línea:https://doaj.org/article/07aa588d8da84ac096066ca3e9327d05
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spelling oai:doaj.org-article:07aa588d8da84ac096066ca3e9327d052021-11-14T09:00:14ZPrevalence of type 2 diabetes mellitus and other abnormalities of carbohydrate metabolism depending on diagnostic criteria2072-03512072-037810.14341/2072-0351-6026https://doaj.org/article/07aa588d8da84ac096066ca3e9327d052010-03-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/6026https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Aim. To assess current criteria for type 2 diabetes mellitus. Materials and methods. This screening study involving 2,368 residents of two municipal districts of the Moscow region was designed to elucidate differencesin the prevalence of abnormalities of carbohydrate metabolism depending on diagnostic criteria (WHO and ADA). Results. The prevalence of early disorders of carbohydrate metabolism and DM2 among the adult population of Moscow region is 17,1 and 7,2 respectivelyusing WHO criteria and 40,0 and 5,9% by ADA criteria. Conclusion. Refusal to undergo OGTT during screening decreases detectability of early metabolic disorders by 28,8 and 6,1% using WHO and ADAcriteria respectively. When screening is aimed to diagnose DM2 alone, OGTT can be omitted in subjects with fasting plasma glucose level below4,7 mmol/l. If it is aimed to diagnose both DM2 and impaired glucose tolerance, OGTT is not needed in subjects with fasting plasma glucose levelbelow 4,2 mmol/l. The use of ?combined? diagnostic criteria (i.e. OGTT according to ADA, but not WHO) significantly increases the prevalence ofmetabolic disorders from 24,9 to 48,8%.Alexander Vasil'evich Dreval'Inna Vladimirovna MisnikovaIl'ya Alexeevich BarsukovGalina Vladimirovna PonchakovaAnatoliy Vasil'evich KuznetsovEndocrinology Research Centrearticlediabetes mellitusglucose tolerance testimpaired glucose toleranceNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 13, Iss 1, Pp 116-121 (2010)
institution DOAJ
collection DOAJ
language EN
RU
topic diabetes mellitus
glucose tolerance test
impaired glucose tolerance
Nutritional diseases. Deficiency diseases
RC620-627
spellingShingle diabetes mellitus
glucose tolerance test
impaired glucose tolerance
Nutritional diseases. Deficiency diseases
RC620-627
Alexander Vasil'evich Dreval'
Inna Vladimirovna Misnikova
Il'ya Alexeevich Barsukov
Galina Vladimirovna Ponchakova
Anatoliy Vasil'evich Kuznetsov
Prevalence of type 2 diabetes mellitus and other abnormalities of carbohydrate metabolism depending on diagnostic criteria
description Aim. To assess current criteria for type 2 diabetes mellitus. Materials and methods. This screening study involving 2,368 residents of two municipal districts of the Moscow region was designed to elucidate differencesin the prevalence of abnormalities of carbohydrate metabolism depending on diagnostic criteria (WHO and ADA). Results. The prevalence of early disorders of carbohydrate metabolism and DM2 among the adult population of Moscow region is 17,1 and 7,2 respectivelyusing WHO criteria and 40,0 and 5,9% by ADA criteria. Conclusion. Refusal to undergo OGTT during screening decreases detectability of early metabolic disorders by 28,8 and 6,1% using WHO and ADAcriteria respectively. When screening is aimed to diagnose DM2 alone, OGTT can be omitted in subjects with fasting plasma glucose level below4,7 mmol/l. If it is aimed to diagnose both DM2 and impaired glucose tolerance, OGTT is not needed in subjects with fasting plasma glucose levelbelow 4,2 mmol/l. The use of ?combined? diagnostic criteria (i.e. OGTT according to ADA, but not WHO) significantly increases the prevalence ofmetabolic disorders from 24,9 to 48,8%.
format article
author Alexander Vasil'evich Dreval'
Inna Vladimirovna Misnikova
Il'ya Alexeevich Barsukov
Galina Vladimirovna Ponchakova
Anatoliy Vasil'evich Kuznetsov
author_facet Alexander Vasil'evich Dreval'
Inna Vladimirovna Misnikova
Il'ya Alexeevich Barsukov
Galina Vladimirovna Ponchakova
Anatoliy Vasil'evich Kuznetsov
author_sort Alexander Vasil'evich Dreval'
title Prevalence of type 2 diabetes mellitus and other abnormalities of carbohydrate metabolism depending on diagnostic criteria
title_short Prevalence of type 2 diabetes mellitus and other abnormalities of carbohydrate metabolism depending on diagnostic criteria
title_full Prevalence of type 2 diabetes mellitus and other abnormalities of carbohydrate metabolism depending on diagnostic criteria
title_fullStr Prevalence of type 2 diabetes mellitus and other abnormalities of carbohydrate metabolism depending on diagnostic criteria
title_full_unstemmed Prevalence of type 2 diabetes mellitus and other abnormalities of carbohydrate metabolism depending on diagnostic criteria
title_sort prevalence of type 2 diabetes mellitus and other abnormalities of carbohydrate metabolism depending on diagnostic criteria
publisher Endocrinology Research Centre
publishDate 2010
url https://doaj.org/article/07aa588d8da84ac096066ca3e9327d05
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