Subsynaptic Distribution, Lipid Raft Targeting and G Protein-Dependent Signalling of the Type 1 Cannabinoid Receptor in Synaptosomes from the Mouse Hippocampus and Frontal Cortex

Subsynaptic Distribution, Lipid Raft Targeting and G Protein-Dependent Signalling of the Type 1 Cannabinoid Receptor in Synaptosomes from the Mouse Hippocampus and Frontal Cortex

Numerous studies have investigated the roles of the type 1 cannabinoid receptor (CB1) in glutamatergic and GABAergic neurons. Here, we used the cell-type-specific CB1 rescue model in mice to gain insight into the organizational principles of plasma membrane targeting and Gαi/o protein signalling of...

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Bibliographic Details
Main Authors: Miquel Saumell-Esnaola, Sergio Barrondo, Gontzal García del Caño, María Aranzazu Goicolea, Joan Sallés, Beat Lutz, Krisztina Monory
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
type 1 cannabinoid receptor CB1
cholesterol
hippocampus
frontal cortex
synaptosomes
rescue model
Organic chemistry
QD241-441
Online Access:https://doaj.org/article/07b426a064de4ede87720ba85677203f
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https://doaj.org/article/07b426a064de4ede87720ba85677203f

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