Hyperoxia causes miR-34a-mediated injury via angiopoietin-1 in neonatal lungs

Hyperoxia causes miR-34a-mediated injury via angiopoietin-1 in neonatal lungs

Hyperoxia contributes to lung injury in bronchopulmonary dysplasia. The authors show that hyperoxia increases miR-34a expression in human neonates and in mouse models, and that pathology is ameliorated by miR-34a inhibition or by administration of its target angiopoietin-1

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Autores principales: Mansoor Syed, Pragnya Das, Aishwarya Pawar, Zubair H. Aghai, Anu Kaskinen, Zhen W. Zhuang, Namasivayam Ambalavanan, Gloria Pryhuber, Sture Andersson, Vineet Bhandari
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/07b4800df67744dba5821b2723760dca
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spelling oai:doaj.org-article:07b4800df67744dba5821b2723760dca2021-12-02T14:42:41ZHyperoxia causes miR-34a-mediated injury via angiopoietin-1 in neonatal lungs10.1038/s41467-017-01349-y2041-1723https://doaj.org/article/07b4800df67744dba5821b2723760dca2017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01349-yhttps://doaj.org/toc/2041-1723Hyperoxia contributes to lung injury in bronchopulmonary dysplasia. The authors show that hyperoxia increases miR-34a expression in human neonates and in mouse models, and that pathology is ameliorated by miR-34a inhibition or by administration of its target angiopoietin-1Mansoor SyedPragnya DasAishwarya PawarZubair H. AghaiAnu KaskinenZhen W. ZhuangNamasivayam AmbalavananGloria PryhuberSture AnderssonVineet BhandariNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Mansoor Syed
Pragnya Das
Aishwarya Pawar
Zubair H. Aghai
Anu Kaskinen
Zhen W. Zhuang
Namasivayam Ambalavanan
Gloria Pryhuber
Sture Andersson
Vineet Bhandari
Hyperoxia causes miR-34a-mediated injury via angiopoietin-1 in neonatal lungs
description Hyperoxia contributes to lung injury in bronchopulmonary dysplasia. The authors show that hyperoxia increases miR-34a expression in human neonates and in mouse models, and that pathology is ameliorated by miR-34a inhibition or by administration of its target angiopoietin-1
format article
author Mansoor Syed
Pragnya Das
Aishwarya Pawar
Zubair H. Aghai
Anu Kaskinen
Zhen W. Zhuang
Namasivayam Ambalavanan
Gloria Pryhuber
Sture Andersson
Vineet Bhandari
author_facet Mansoor Syed
Pragnya Das
Aishwarya Pawar
Zubair H. Aghai
Anu Kaskinen
Zhen W. Zhuang
Namasivayam Ambalavanan
Gloria Pryhuber
Sture Andersson
Vineet Bhandari
author_sort Mansoor Syed
title Hyperoxia causes miR-34a-mediated injury via angiopoietin-1 in neonatal lungs
title_short Hyperoxia causes miR-34a-mediated injury via angiopoietin-1 in neonatal lungs
title_full Hyperoxia causes miR-34a-mediated injury via angiopoietin-1 in neonatal lungs
title_fullStr Hyperoxia causes miR-34a-mediated injury via angiopoietin-1 in neonatal lungs
title_full_unstemmed Hyperoxia causes miR-34a-mediated injury via angiopoietin-1 in neonatal lungs
title_sort hyperoxia causes mir-34a-mediated injury via angiopoietin-1 in neonatal lungs
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/07b4800df67744dba5821b2723760dca
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AT pragnyadas hyperoxiacausesmir34amediatedinjuryviaangiopoietin1inneonatallungs
AT aishwaryapawar hyperoxiacausesmir34amediatedinjuryviaangiopoietin1inneonatallungs
AT zubairhaghai hyperoxiacausesmir34amediatedinjuryviaangiopoietin1inneonatallungs
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AT namasivayamambalavanan hyperoxiacausesmir34amediatedinjuryviaangiopoietin1inneonatallungs
AT gloriapryhuber hyperoxiacausesmir34amediatedinjuryviaangiopoietin1inneonatallungs
AT stureandersson hyperoxiacausesmir34amediatedinjuryviaangiopoietin1inneonatallungs
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