Expression of molecular lymphatic markers in human choroid
The purpose of this study was to research lymphatic outflow tract in the human choroid. Using a light microscopy and immunohistochemistry, structure of the choroid was investigated. We used antibodies against lymphatic endothelial-specific markers Prox-1, LYVE-1, Podoplanin, endothelial blood vessel...
Guardado en:
| Autor principal: | |
|---|---|
| Formato: | article |
| Lenguaje: | RU |
| Publicado: |
Scientific Сentre for Family Health and Human Reproduction Problems
2016
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/07ba5751072f4855baeb7baeabb1461d |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| Sumario: | The purpose of this study was to research lymphatic outflow tract in the human choroid. Using a light microscopy and immunohistochemistry, structure of the choroid was investigated. We used antibodies against lymphatic endothelial-specific markers Prox-1, LYVE-1, Podoplanin, endothelial blood vessels marker CD34 and fibroblasts growth factor receptor FGFR. The choroid was found to contain lymphatic canals in choroidal stroma and a layer of choriocapillaris, and lymphatic lacunae in the suprachoroid lamina, limited endothelium-like cells, positively stained for markers of lymphatic vessels Prox-1, LYVE-1, Podoplanin, and fibroblasts and pigment cells. These endothelium-like cells were shown positive Prox-1, LYVE-1 and Podoplanin staining and negative CD34 staining; therefore we consider that these canals and lacunae are lymphatic structures. |
|---|