Expression of molecular lymphatic markers in human choroid
The purpose of this study was to research lymphatic outflow tract in the human choroid. Using a light microscopy and immunohistochemistry, structure of the choroid was investigated. We used antibodies against lymphatic endothelial-specific markers Prox-1, LYVE-1, Podoplanin, endothelial blood vessel...
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Scientific Сentre for Family Health and Human Reproduction Problems
2016
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oai:doaj.org-article:07ba5751072f4855baeb7baeabb1461d2021-11-23T06:14:36ZExpression of molecular lymphatic markers in human choroid2541-94202587-959610.12737/23404https://doaj.org/article/07ba5751072f4855baeb7baeabb1461d2016-09-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/290https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The purpose of this study was to research lymphatic outflow tract in the human choroid. Using a light microscopy and immunohistochemistry, structure of the choroid was investigated. We used antibodies against lymphatic endothelial-specific markers Prox-1, LYVE-1, Podoplanin, endothelial blood vessels marker CD34 and fibroblasts growth factor receptor FGFR. The choroid was found to contain lymphatic canals in choroidal stroma and a layer of choriocapillaris, and lymphatic lacunae in the suprachoroid lamina, limited endothelium-like cells, positively stained for markers of lymphatic vessels Prox-1, LYVE-1, Podoplanin, and fibroblasts and pigment cells. These endothelium-like cells were shown positive Prox-1, LYVE-1 and Podoplanin staining and negative CD34 staining; therefore we consider that these canals and lacunae are lymphatic structures.S. R. NogovitsinaScientific Сentre for Family Health and Human Reproduction Problemsarticlechoroidlymphatic lacunaelymphatic channelsScienceQRUActa Biomedica Scientifica, Vol 1, Iss 5, Pp 114-116 (2016) |
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DOAJ |
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DOAJ |
| language |
RU |
| topic |
choroid lymphatic lacunae lymphatic channels Science Q |
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choroid lymphatic lacunae lymphatic channels Science Q S. R. Nogovitsina Expression of molecular lymphatic markers in human choroid |
| description |
The purpose of this study was to research lymphatic outflow tract in the human choroid. Using a light microscopy and immunohistochemistry, structure of the choroid was investigated. We used antibodies against lymphatic endothelial-specific markers Prox-1, LYVE-1, Podoplanin, endothelial blood vessels marker CD34 and fibroblasts growth factor receptor FGFR. The choroid was found to contain lymphatic canals in choroidal stroma and a layer of choriocapillaris, and lymphatic lacunae in the suprachoroid lamina, limited endothelium-like cells, positively stained for markers of lymphatic vessels Prox-1, LYVE-1, Podoplanin, and fibroblasts and pigment cells. These endothelium-like cells were shown positive Prox-1, LYVE-1 and Podoplanin staining and negative CD34 staining; therefore we consider that these canals and lacunae are lymphatic structures. |
| format |
article |
| author |
S. R. Nogovitsina |
| author_facet |
S. R. Nogovitsina |
| author_sort |
S. R. Nogovitsina |
| title |
Expression of molecular lymphatic markers in human choroid |
| title_short |
Expression of molecular lymphatic markers in human choroid |
| title_full |
Expression of molecular lymphatic markers in human choroid |
| title_fullStr |
Expression of molecular lymphatic markers in human choroid |
| title_full_unstemmed |
Expression of molecular lymphatic markers in human choroid |
| title_sort |
expression of molecular lymphatic markers in human choroid |
| publisher |
Scientific Сentre for Family Health and Human Reproduction Problems |
| publishDate |
2016 |
| url |
https://doaj.org/article/07ba5751072f4855baeb7baeabb1461d |
| work_keys_str_mv |
AT srnogovitsina expressionofmolecularlymphaticmarkersinhumanchoroid |
| _version_ |
1718416989299408896 |