Robustness and lethality in multilayer biological molecular networks
Robustness is a prominent feature of most biological systems, but most of the current efforts have been focused on studying homogeneous molecular networks. Here the authors propose a comprehensive framework for understanding how the interactions between genes, proteins, and metabolites contribute to...
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Nature Portfolio
2020
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oai:doaj.org-article:07c2f37c5d30453babf20426c0d4165d2021-12-02T16:49:28ZRobustness and lethality in multilayer biological molecular networks10.1038/s41467-020-19841-32041-1723https://doaj.org/article/07c2f37c5d30453babf20426c0d4165d2020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19841-3https://doaj.org/toc/2041-1723Robustness is a prominent feature of most biological systems, but most of the current efforts have been focused on studying homogeneous molecular networks. Here the authors propose a comprehensive framework for understanding how the interactions between genes, proteins, and metabolites contribute to the determinants of robustness.Xueming LiuEnrico MaiorinoArda HaluKimberly GlassRashmi B. PrasadJoseph LoscalzoJianxi GaoAmitabh SharmaNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020) |
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Science Q Xueming Liu Enrico Maiorino Arda Halu Kimberly Glass Rashmi B. Prasad Joseph Loscalzo Jianxi Gao Amitabh Sharma Robustness and lethality in multilayer biological molecular networks |
description |
Robustness is a prominent feature of most biological systems, but most of the current efforts have been focused on studying homogeneous molecular networks. Here the authors propose a comprehensive framework for understanding how the interactions between genes, proteins, and metabolites contribute to the determinants of robustness. |
format |
article |
author |
Xueming Liu Enrico Maiorino Arda Halu Kimberly Glass Rashmi B. Prasad Joseph Loscalzo Jianxi Gao Amitabh Sharma |
author_facet |
Xueming Liu Enrico Maiorino Arda Halu Kimberly Glass Rashmi B. Prasad Joseph Loscalzo Jianxi Gao Amitabh Sharma |
author_sort |
Xueming Liu |
title |
Robustness and lethality in multilayer biological molecular networks |
title_short |
Robustness and lethality in multilayer biological molecular networks |
title_full |
Robustness and lethality in multilayer biological molecular networks |
title_fullStr |
Robustness and lethality in multilayer biological molecular networks |
title_full_unstemmed |
Robustness and lethality in multilayer biological molecular networks |
title_sort |
robustness and lethality in multilayer biological molecular networks |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/07c2f37c5d30453babf20426c0d4165d |
work_keys_str_mv |
AT xuemingliu robustnessandlethalityinmultilayerbiologicalmolecularnetworks AT enricomaiorino robustnessandlethalityinmultilayerbiologicalmolecularnetworks AT ardahalu robustnessandlethalityinmultilayerbiologicalmolecularnetworks AT kimberlyglass robustnessandlethalityinmultilayerbiologicalmolecularnetworks AT rashmibprasad robustnessandlethalityinmultilayerbiologicalmolecularnetworks AT josephloscalzo robustnessandlethalityinmultilayerbiologicalmolecularnetworks AT jianxigao robustnessandlethalityinmultilayerbiologicalmolecularnetworks AT amitabhsharma robustnessandlethalityinmultilayerbiologicalmolecularnetworks |
_version_ |
1718383316074233856 |