Structural mechanism underlying primary and secondary coupling between GPCRs and the Gi/o family
G protein-coupled receptors (GPCRs) can couple to more than one G protein subtype, and the coupling efficiency varies depending on the GPCR-G protein pair. Here authors use hydrogen/deuterium exchange mass spectrometry and mutagenesis to study the structural mechanism underlying primary and secondar...
Guardado en:
Autores principales: | Hee Ryung Kim, Jun Xu, Shoji Maeda, Nguyen Minh Duc, Donghoon Ahn, Yang Du, Ka Young Chung |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/07c8ff45757c4596b553213efaff5436 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Local membrane charge regulates β2 adrenergic receptor coupling to Gi3
por: M. J. Strohman, et al.
Publicado: (2019) -
Roles of G Protein-Coupled Receptors (GPCRs) in Gastrointestinal Cancers: Focus on Sphingosine 1-Shosphate Receptors, Angiotensin II Receptors, and Estrogen-Related GPCRs
por: Zhen Zeng, et al.
Publicado: (2021) -
The origin of GPCRs: identification of mammalian like Rhodopsin, Adhesion, Glutamate and Frizzled GPCRs in fungi.
por: Arunkumar Krishnan, et al.
Publicado: (2012) -
GI Bill of Rights, 1944
Publicado: (2017) -
Super-complexes of adhesion GPCRs and neural guidance receptors
por: Verity A. Jackson, et al.
Publicado: (2016)