Current epidemiological situation on leptospirosis in the territories adjacent to Lake Baikal

Background. In presence the epizootiological situation on leptospirosis in the territories adjacent to Lake Baikal is not studied well. The showing up of natural focus, discovering of host animal’s species composition and etiological structure of leptospirosis causative agents are essential to plan...

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Autores principales:	E. Yu. Kiseleva, V. M. Korzun, S. A. Borisov, N. V. Breneva, A. F. Timoshenko, M. B. Sharakshanov, S. V. Balakhonov
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2021
Materias:	leptospirosis epizootological survey small mammals the territories adjacent to lake baikal Science Q
Acceso en línea:	https://doaj.org/article/07cdb7b161184666956539c4589404b4
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spelling	oai:doaj.org-article:07cdb7b161184666956539c4589404b42021-11-23T06:14:46ZCurrent epidemiological situation on leptospirosis in the territories adjacent to Lake Baikal2541-94202587-959610.29413/ABS.2021-6.5.6https://doaj.org/article/07cdb7b161184666956539c4589404b42021-11-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/3030https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Background. In presence the epizootiological situation on leptospirosis in the territories adjacent to Lake Baikal is not studied well. The showing up of natural focus, discovering of host animal’s species composition and etiological structure of leptospirosis causative agents are essential to plan any epidemiological response and to organize the specific prophylaxis.Aim: to analyze contemporary characteristics of leptospirosis natural foci at the territories adjacent to Lake Baikal.Materials and methods. From 2011 till 2020 the territory of nine Irkutsk Region's administrative districts was investigated. Trapping has been done at four kind of sites (wetland, meadow, forest-shrub, steppificated meadow) and boroughs. 1152 small mammals which belonged to 35 species were collected. Collected samples were studied by complex of methods. Serogroup belonging was detected by micro agglutination and decomposition test, and genomic species – by Microflex LT mass analyzer.Results. A leptospirosis natural foci in the Irkutsk city boundary was newly founded and there were isolated (from small mammals) four pathogenic cultures of leptospiras belonging to Javanica serogroup. Main hosts of causative agents at the territories adjacent to Lake Baikal were defined (insect-eating mammals: tundra shrew, largetoothed Siberian shrew, even-toothed shrew, shrew-mouse, and rodents: root vole, ground vole, narrow-skulled vole, sewer rat). By micro agglutination were defined pathogenic leptospirosis serogroups (Icterohaemorrhagiae, Grippotyphosa, Javanica, Pomona, Sejroe, Autumnalis, Australis), all over 2.4 ± 0.45 % seropositive. Antibody dilution at survey animals ranged from 1 : 20 to 1 : 640. On the grounds of PCR results the mean value of infected animals in studied sample was 16.4 ± 1.14 %. Positive PCR findings were at 19 from 35 animal species.Conclusion. At the territories adjacent to Lake Baikal In the Baikal region, the proportion of animals that have had contact with pathogenic leptospira is quite high. Natural focus of this infection are highly pervasive in this region, they are evolved mainly in dewy sites.E. Yu. KiselevaV. M. KorzunS. A. BorisovN. V. BrenevaA. F. TimoshenkoM. B. SharakshanovS. V. BalakhonovScientific Сentre for Family Health and Human Reproduction Problemsarticleleptospirosisepizootological surveysmall mammalsthe territories adjacent to lake baikalScienceQRUActa Biomedica Scientifica, Vol 6, Iss 5, Pp 57-67 (2021)
institution	DOAJ
collection	DOAJ
language	RU
topic	leptospirosis epizootological survey small mammals the territories adjacent to lake baikal Science Q
spellingShingle	leptospirosis epizootological survey small mammals the territories adjacent to lake baikal Science Q E. Yu. Kiseleva V. M. Korzun S. A. Borisov N. V. Breneva A. F. Timoshenko M. B. Sharakshanov S. V. Balakhonov Current epidemiological situation on leptospirosis in the territories adjacent to Lake Baikal
description	Background. In presence the epizootiological situation on leptospirosis in the territories adjacent to Lake Baikal is not studied well. The showing up of natural focus, discovering of host animal’s species composition and etiological structure of leptospirosis causative agents are essential to plan any epidemiological response and to organize the specific prophylaxis.Aim: to analyze contemporary characteristics of leptospirosis natural foci at the territories adjacent to Lake Baikal.Materials and methods. From 2011 till 2020 the territory of nine Irkutsk Region's administrative districts was investigated. Trapping has been done at four kind of sites (wetland, meadow, forest-shrub, steppificated meadow) and boroughs. 1152 small mammals which belonged to 35 species were collected. Collected samples were studied by complex of methods. Serogroup belonging was detected by micro agglutination and decomposition test, and genomic species – by Microflex LT mass analyzer.Results. A leptospirosis natural foci in the Irkutsk city boundary was newly founded and there were isolated (from small mammals) four pathogenic cultures of leptospiras belonging to Javanica serogroup. Main hosts of causative agents at the territories adjacent to Lake Baikal were defined (insect-eating mammals: tundra shrew, largetoothed Siberian shrew, even-toothed shrew, shrew-mouse, and rodents: root vole, ground vole, narrow-skulled vole, sewer rat). By micro agglutination were defined pathogenic leptospirosis serogroups (Icterohaemorrhagiae, Grippotyphosa, Javanica, Pomona, Sejroe, Autumnalis, Australis), all over 2.4 ± 0.45 % seropositive. Antibody dilution at survey animals ranged from 1 : 20 to 1 : 640. On the grounds of PCR results the mean value of infected animals in studied sample was 16.4 ± 1.14 %. Positive PCR findings were at 19 from 35 animal species.Conclusion. At the territories adjacent to Lake Baikal In the Baikal region, the proportion of animals that have had contact with pathogenic leptospira is quite high. Natural focus of this infection are highly pervasive in this region, they are evolved mainly in dewy sites.
format	article
author	E. Yu. Kiseleva V. M. Korzun S. A. Borisov N. V. Breneva A. F. Timoshenko M. B. Sharakshanov S. V. Balakhonov
author_facet	E. Yu. Kiseleva V. M. Korzun S. A. Borisov N. V. Breneva A. F. Timoshenko M. B. Sharakshanov S. V. Balakhonov
author_sort	E. Yu. Kiseleva
title	Current epidemiological situation on leptospirosis in the territories adjacent to Lake Baikal
title_short	Current epidemiological situation on leptospirosis in the territories adjacent to Lake Baikal
title_full	Current epidemiological situation on leptospirosis in the territories adjacent to Lake Baikal
title_fullStr	Current epidemiological situation on leptospirosis in the territories adjacent to Lake Baikal
title_full_unstemmed	Current epidemiological situation on leptospirosis in the territories adjacent to Lake Baikal
title_sort	current epidemiological situation on leptospirosis in the territories adjacent to lake baikal
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2021
url	https://doaj.org/article/07cdb7b161184666956539c4589404b4
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Current epidemiological situation on leptospirosis in the territories adjacent to Lake Baikal

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