Comprehensive micro-scaled proteome and phosphoproteome characterization of archived retrospective cancer repositories

Formalin-fixed, paraffin-embedded (FFPE) specimens are an attractive resource for retrospective clinical proteomics studies. Here, the authors benchmark and optimize proteomics workflows for FFPE sample analysis and provide guidelines on which methods to use for different samples and applications.

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Autores principales:	Corinna Friedrich, Simon Schallenberg, Marieluise Kirchner, Matthias Ziehm, Sylvia Niquet, Mohamed Haji, Christin Beier, Jens Neudecker, Frederick Klauschen, Philipp Mertins
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/07d769ebf707411881a2ed4527cea37b
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spelling	oai:doaj.org-article:07d769ebf707411881a2ed4527cea37b2021-12-02T17:30:39ZComprehensive micro-scaled proteome and phosphoproteome characterization of archived retrospective cancer repositories10.1038/s41467-021-23855-w2041-1723https://doaj.org/article/07d769ebf707411881a2ed4527cea37b2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23855-whttps://doaj.org/toc/2041-1723Formalin-fixed, paraffin-embedded (FFPE) specimens are an attractive resource for retrospective clinical proteomics studies. Here, the authors benchmark and optimize proteomics workflows for FFPE sample analysis and provide guidelines on which methods to use for different samples and applications.Corinna FriedrichSimon SchallenbergMarieluise KirchnerMatthias ZiehmSylvia NiquetMohamed HajiChristin BeierJens NeudeckerFrederick KlauschenPhilipp MertinsNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Corinna Friedrich Simon Schallenberg Marieluise Kirchner Matthias Ziehm Sylvia Niquet Mohamed Haji Christin Beier Jens Neudecker Frederick Klauschen Philipp Mertins Comprehensive micro-scaled proteome and phosphoproteome characterization of archived retrospective cancer repositories
description	Formalin-fixed, paraffin-embedded (FFPE) specimens are an attractive resource for retrospective clinical proteomics studies. Here, the authors benchmark and optimize proteomics workflows for FFPE sample analysis and provide guidelines on which methods to use for different samples and applications.
format	article
author	Corinna Friedrich Simon Schallenberg Marieluise Kirchner Matthias Ziehm Sylvia Niquet Mohamed Haji Christin Beier Jens Neudecker Frederick Klauschen Philipp Mertins
author_facet	Corinna Friedrich Simon Schallenberg Marieluise Kirchner Matthias Ziehm Sylvia Niquet Mohamed Haji Christin Beier Jens Neudecker Frederick Klauschen Philipp Mertins
author_sort	Corinna Friedrich
title	Comprehensive micro-scaled proteome and phosphoproteome characterization of archived retrospective cancer repositories
title_short	Comprehensive micro-scaled proteome and phosphoproteome characterization of archived retrospective cancer repositories
title_full	Comprehensive micro-scaled proteome and phosphoproteome characterization of archived retrospective cancer repositories
title_fullStr	Comprehensive micro-scaled proteome and phosphoproteome characterization of archived retrospective cancer repositories
title_full_unstemmed	Comprehensive micro-scaled proteome and phosphoproteome characterization of archived retrospective cancer repositories
title_sort	comprehensive micro-scaled proteome and phosphoproteome characterization of archived retrospective cancer repositories
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/07d769ebf707411881a2ed4527cea37b
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Comprehensive micro-scaled proteome and phosphoproteome characterization of archived retrospective cancer repositories

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