Effects of Microgravity on Early Embryonic Development and Embryonic Stem Cell Differentiation: Phenotypic Characterization and Potential Mechanisms

With the development of science and technology, mankind’s exploration of outer space has increased tremendously. Settling in outer space or on other planets could help solve the Earth’s resource crisis, but such settlement will first face the problem of reproduction. There are considerable differenc...

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Autores principales:	Feng Li, Ying Ye, Xiaohua Lei, Wensheng Zhang
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	microgravity ES cells differentiation self-renewal embryonic developement Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/07dcf4d1f1b141f3b5ad2f022d27fa8c
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id	oai:doaj.org-article:07dcf4d1f1b141f3b5ad2f022d27fa8c
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spelling	oai:doaj.org-article:07dcf4d1f1b141f3b5ad2f022d27fa8c2021-12-02T10:48:33ZEffects of Microgravity on Early Embryonic Development and Embryonic Stem Cell Differentiation: Phenotypic Characterization and Potential Mechanisms2296-634X10.3389/fcell.2021.797167https://doaj.org/article/07dcf4d1f1b141f3b5ad2f022d27fa8c2021-12-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fcell.2021.797167/fullhttps://doaj.org/toc/2296-634XWith the development of science and technology, mankind’s exploration of outer space has increased tremendously. Settling in outer space or on other planets could help solve the Earth’s resource crisis, but such settlement will first face the problem of reproduction. There are considerable differences between outer space and the Earth’s environment, with the effects of gravity being one of the most significant. Studying the possible effects and underlying mechanisms of microgravity on embryonic stem cell (ESC) differentiation and embryonic development could help provide solutions to healthy living and reproduction in deep space. This article summarizes recent research progress on the effects of microgravity on ESCs and early embryonic development and proposes hypotheses regarding the potential mechanisms. In addition, we discuss the controversies and key questions in the field and indicate directions for future research.Feng LiYing YeXiaohua LeiWensheng ZhangWensheng ZhangFrontiers Media S.A.articlemicrogravityES cellsdifferentiationself-renewalembryonic developementBiology (General)QH301-705.5ENFrontiers in Cell and Developmental Biology, Vol 9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	microgravity ES cells differentiation self-renewal embryonic developement Biology (General) QH301-705.5
spellingShingle	microgravity ES cells differentiation self-renewal embryonic developement Biology (General) QH301-705.5 Feng Li Ying Ye Xiaohua Lei Wensheng Zhang Wensheng Zhang Effects of Microgravity on Early Embryonic Development and Embryonic Stem Cell Differentiation: Phenotypic Characterization and Potential Mechanisms
description	With the development of science and technology, mankind’s exploration of outer space has increased tremendously. Settling in outer space or on other planets could help solve the Earth’s resource crisis, but such settlement will first face the problem of reproduction. There are considerable differences between outer space and the Earth’s environment, with the effects of gravity being one of the most significant. Studying the possible effects and underlying mechanisms of microgravity on embryonic stem cell (ESC) differentiation and embryonic development could help provide solutions to healthy living and reproduction in deep space. This article summarizes recent research progress on the effects of microgravity on ESCs and early embryonic development and proposes hypotheses regarding the potential mechanisms. In addition, we discuss the controversies and key questions in the field and indicate directions for future research.
format	article
author	Feng Li Ying Ye Xiaohua Lei Wensheng Zhang Wensheng Zhang
author_facet	Feng Li Ying Ye Xiaohua Lei Wensheng Zhang Wensheng Zhang
author_sort	Feng Li
title	Effects of Microgravity on Early Embryonic Development and Embryonic Stem Cell Differentiation: Phenotypic Characterization and Potential Mechanisms
title_short	Effects of Microgravity on Early Embryonic Development and Embryonic Stem Cell Differentiation: Phenotypic Characterization and Potential Mechanisms
title_full	Effects of Microgravity on Early Embryonic Development and Embryonic Stem Cell Differentiation: Phenotypic Characterization and Potential Mechanisms
title_fullStr	Effects of Microgravity on Early Embryonic Development and Embryonic Stem Cell Differentiation: Phenotypic Characterization and Potential Mechanisms
title_full_unstemmed	Effects of Microgravity on Early Embryonic Development and Embryonic Stem Cell Differentiation: Phenotypic Characterization and Potential Mechanisms
title_sort	effects of microgravity on early embryonic development and embryonic stem cell differentiation: phenotypic characterization and potential mechanisms
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/07dcf4d1f1b141f3b5ad2f022d27fa8c
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_version_	1718396569185681408

Effects of Microgravity on Early Embryonic Development and Embryonic Stem Cell Differentiation: Phenotypic Characterization and Potential Mechanisms

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