Antiarthritic Activities of Herbal Isolates: A Comprehensive Review

Numerous plant isolates with therapeutic properties, such as antimicrobial, antiinflammatory, antiviral, antimalarial, antiarthritic (AA), hepatoprotective, cardiotonic, and so forth, are reported in the literature. Usually, medicinal plants are widely used, and assumed to be safe and cheaper altern...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Shweta Jain, Ankur Vaidya, Pawan Kumar Gupta, Jessica M. Rosenholm, Kuldeep K. Bansal
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	arthritis herbal isolates arthritic models alkaloids terpenoids flavonoids Engineering (General). Civil engineering (General) TA1-2040
Acceso en línea:	https://doaj.org/article/07dfd5654493437c9b4a06d0bb55bb19
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:07dfd5654493437c9b4a06d0bb55bb19
record_format	dspace
spelling	oai:doaj.org-article:07dfd5654493437c9b4a06d0bb55bb192021-11-25T17:16:05ZAntiarthritic Activities of Herbal Isolates: A Comprehensive Review10.3390/coatings111113292079-6412https://doaj.org/article/07dfd5654493437c9b4a06d0bb55bb192021-10-01T00:00:00Zhttps://www.mdpi.com/2079-6412/11/11/1329https://doaj.org/toc/2079-6412Numerous plant isolates with therapeutic properties, such as antimicrobial, antiinflammatory, antiviral, antimalarial, antiarthritic (AA), hepatoprotective, cardiotonic, and so forth, are reported in the literature. Usually, medicinal plants are widely used, and assumed to be safe and cheaper alternatives to chemically synthesized drugs. However, they are not regulated for potency and purity, and thus care must be taken for their safe use. In this review, we aimed to compile all of the herbal isolates possessing AA properties, including alkaloids (montanine, 3-acetylaconitine, sanguinarine, jatrorrhizine hydrochloride, and piperine), terpenoids (eugenol, nimbolide, bartogenic acid, cannabidiol, and curcumin), and flavonoids (quercetin, resveratrol, kaempferol, chebulanin, ellagic acid, rosmarinic acid, gallic acid, chlorogenic acid, ferulic acid, and brazilin). These isolates act through numerous pharmacological mechanisms such as inhibiting cytokines, chemokines, or matrix metalloproteinase, etc., to demonstrate AA activity. Animal models utilized for assessing the AA properties of these isolates, including adjuvant-induced arthritis mouse models, are also discussed. Furthermore, nanotechnology-based approaches to deliver these isolates are also reviewed, which have shown improved therapeutic efficacy of isolated compounds.Shweta JainAnkur VaidyaPawan Kumar GuptaJessica M. RosenholmKuldeep K. BansalMDPI AGarticlearthritisherbal isolatesarthritic modelsalkaloidsterpenoidsflavonoidsEngineering (General). Civil engineering (General)TA1-2040ENCoatings, Vol 11, Iss 1329, p 1329 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	arthritis herbal isolates arthritic models alkaloids terpenoids flavonoids Engineering (General). Civil engineering (General) TA1-2040
spellingShingle	arthritis herbal isolates arthritic models alkaloids terpenoids flavonoids Engineering (General). Civil engineering (General) TA1-2040 Shweta Jain Ankur Vaidya Pawan Kumar Gupta Jessica M. Rosenholm Kuldeep K. Bansal Antiarthritic Activities of Herbal Isolates: A Comprehensive Review
description	Numerous plant isolates with therapeutic properties, such as antimicrobial, antiinflammatory, antiviral, antimalarial, antiarthritic (AA), hepatoprotective, cardiotonic, and so forth, are reported in the literature. Usually, medicinal plants are widely used, and assumed to be safe and cheaper alternatives to chemically synthesized drugs. However, they are not regulated for potency and purity, and thus care must be taken for their safe use. In this review, we aimed to compile all of the herbal isolates possessing AA properties, including alkaloids (montanine, 3-acetylaconitine, sanguinarine, jatrorrhizine hydrochloride, and piperine), terpenoids (eugenol, nimbolide, bartogenic acid, cannabidiol, and curcumin), and flavonoids (quercetin, resveratrol, kaempferol, chebulanin, ellagic acid, rosmarinic acid, gallic acid, chlorogenic acid, ferulic acid, and brazilin). These isolates act through numerous pharmacological mechanisms such as inhibiting cytokines, chemokines, or matrix metalloproteinase, etc., to demonstrate AA activity. Animal models utilized for assessing the AA properties of these isolates, including adjuvant-induced arthritis mouse models, are also discussed. Furthermore, nanotechnology-based approaches to deliver these isolates are also reviewed, which have shown improved therapeutic efficacy of isolated compounds.
format	article
author	Shweta Jain Ankur Vaidya Pawan Kumar Gupta Jessica M. Rosenholm Kuldeep K. Bansal
author_facet	Shweta Jain Ankur Vaidya Pawan Kumar Gupta Jessica M. Rosenholm Kuldeep K. Bansal
author_sort	Shweta Jain
title	Antiarthritic Activities of Herbal Isolates: A Comprehensive Review
title_short	Antiarthritic Activities of Herbal Isolates: A Comprehensive Review
title_full	Antiarthritic Activities of Herbal Isolates: A Comprehensive Review
title_fullStr	Antiarthritic Activities of Herbal Isolates: A Comprehensive Review
title_full_unstemmed	Antiarthritic Activities of Herbal Isolates: A Comprehensive Review
title_sort	antiarthritic activities of herbal isolates: a comprehensive review
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/07dfd5654493437c9b4a06d0bb55bb19
work_keys_str_mv	AT shwetajain antiarthriticactivitiesofherbalisolatesacomprehensivereview AT ankurvaidya antiarthriticactivitiesofherbalisolatesacomprehensivereview AT pawankumargupta antiarthriticactivitiesofherbalisolatesacomprehensivereview AT jessicamrosenholm antiarthriticactivitiesofherbalisolatesacomprehensivereview AT kuldeepkbansal antiarthriticactivitiesofherbalisolatesacomprehensivereview
_version_	1718412509832019968

Antiarthritic Activities of Herbal Isolates: A Comprehensive Review

Ejemplares similares