Light-mediated discovery of surfaceome nanoscale organization and intercellular receptor interaction networks

The spatial organization of cell surface receptors is critical for cell signaling and drug action. Here, the authors develop an optoproteomic method for mapping surface protein interactions, revealing cellular responses to antibodies, drugs and viral particles as well as immunosynapse signaling even...

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Autores principales:	Maik Müller, Fabienne Gräbnitz, Niculò Barandun, Yang Shen, Fabian Wendt, Sebastian N. Steiner, Yannik Severin, Stefan U. Vetterli, Milon Mondal, James R. Prudent, Raphael Hofmann, Marc van Oostrum, Roman C. Sarott, Alexey I. Nesvizhskii, Erick M. Carreira, Jeffrey W. Bode, Berend Snijder, John A. Robinson, Martin J. Loessner, Annette Oxenius, Bernd Wollscheid
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/07e4f618935147f798b726c0fe3eb3c4
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spelling	oai:doaj.org-article:07e4f618935147f798b726c0fe3eb3c42021-12-05T12:22:29ZLight-mediated discovery of surfaceome nanoscale organization and intercellular receptor interaction networks10.1038/s41467-021-27280-x2041-1723https://doaj.org/article/07e4f618935147f798b726c0fe3eb3c42021-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-27280-xhttps://doaj.org/toc/2041-1723The spatial organization of cell surface receptors is critical for cell signaling and drug action. Here, the authors develop an optoproteomic method for mapping surface protein interactions, revealing cellular responses to antibodies, drugs and viral particles as well as immunosynapse signaling events.Maik MüllerFabienne GräbnitzNiculò BarandunYang ShenFabian WendtSebastian N. SteinerYannik SeverinStefan U. VetterliMilon MondalJames R. PrudentRaphael HofmannMarc van OostrumRoman C. SarottAlexey I. NesvizhskiiErick M. CarreiraJeffrey W. BodeBerend SnijderJohn A. RobinsonMartin J. LoessnerAnnette OxeniusBernd WollscheidNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Maik Müller Fabienne Gräbnitz Niculò Barandun Yang Shen Fabian Wendt Sebastian N. Steiner Yannik Severin Stefan U. Vetterli Milon Mondal James R. Prudent Raphael Hofmann Marc van Oostrum Roman C. Sarott Alexey I. Nesvizhskii Erick M. Carreira Jeffrey W. Bode Berend Snijder John A. Robinson Martin J. Loessner Annette Oxenius Bernd Wollscheid Light-mediated discovery of surfaceome nanoscale organization and intercellular receptor interaction networks
description	The spatial organization of cell surface receptors is critical for cell signaling and drug action. Here, the authors develop an optoproteomic method for mapping surface protein interactions, revealing cellular responses to antibodies, drugs and viral particles as well as immunosynapse signaling events.
format	article
author	Maik Müller Fabienne Gräbnitz Niculò Barandun Yang Shen Fabian Wendt Sebastian N. Steiner Yannik Severin Stefan U. Vetterli Milon Mondal James R. Prudent Raphael Hofmann Marc van Oostrum Roman C. Sarott Alexey I. Nesvizhskii Erick M. Carreira Jeffrey W. Bode Berend Snijder John A. Robinson Martin J. Loessner Annette Oxenius Bernd Wollscheid
author_facet	Maik Müller Fabienne Gräbnitz Niculò Barandun Yang Shen Fabian Wendt Sebastian N. Steiner Yannik Severin Stefan U. Vetterli Milon Mondal James R. Prudent Raphael Hofmann Marc van Oostrum Roman C. Sarott Alexey I. Nesvizhskii Erick M. Carreira Jeffrey W. Bode Berend Snijder John A. Robinson Martin J. Loessner Annette Oxenius Bernd Wollscheid
author_sort	Maik Müller
title	Light-mediated discovery of surfaceome nanoscale organization and intercellular receptor interaction networks
title_short	Light-mediated discovery of surfaceome nanoscale organization and intercellular receptor interaction networks
title_full	Light-mediated discovery of surfaceome nanoscale organization and intercellular receptor interaction networks
title_fullStr	Light-mediated discovery of surfaceome nanoscale organization and intercellular receptor interaction networks
title_full_unstemmed	Light-mediated discovery of surfaceome nanoscale organization and intercellular receptor interaction networks
title_sort	light-mediated discovery of surfaceome nanoscale organization and intercellular receptor interaction networks
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/07e4f618935147f798b726c0fe3eb3c4
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Light-mediated discovery of surfaceome nanoscale organization and intercellular receptor interaction networks

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