Integrative reconstruction of cancer genome karyotypes using InfoGenomeR

Karyotyping of cancer genomes at the base-level is technically challenging. Here, the authors introduce InfoGenomeR, an algorithm that can infer cancer genome karyotypes from whole-genome sequencing data, and test their model on breast, ovarian and brain cancer samples; and identify private and shar...

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Autores principales:	Yeonghun Lee, Hyunju Lee
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/07eb649ab8d84331b7a259b6fb709d4e
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id	oai:doaj.org-article:07eb649ab8d84331b7a259b6fb709d4e
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spelling	oai:doaj.org-article:07eb649ab8d84331b7a259b6fb709d4e2021-12-02T16:55:53ZIntegrative reconstruction of cancer genome karyotypes using InfoGenomeR10.1038/s41467-021-22671-62041-1723https://doaj.org/article/07eb649ab8d84331b7a259b6fb709d4e2021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22671-6https://doaj.org/toc/2041-1723Karyotyping of cancer genomes at the base-level is technically challenging. Here, the authors introduce InfoGenomeR, an algorithm that can infer cancer genome karyotypes from whole-genome sequencing data, and test their model on breast, ovarian and brain cancer samples; and identify private and shared mutations between primary and metastatic cancer samples.Yeonghun LeeHyunju LeeNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yeonghun Lee Hyunju Lee Integrative reconstruction of cancer genome karyotypes using InfoGenomeR
description	Karyotyping of cancer genomes at the base-level is technically challenging. Here, the authors introduce InfoGenomeR, an algorithm that can infer cancer genome karyotypes from whole-genome sequencing data, and test their model on breast, ovarian and brain cancer samples; and identify private and shared mutations between primary and metastatic cancer samples.
format	article
author	Yeonghun Lee Hyunju Lee
author_facet	Yeonghun Lee Hyunju Lee
author_sort	Yeonghun Lee
title	Integrative reconstruction of cancer genome karyotypes using InfoGenomeR
title_short	Integrative reconstruction of cancer genome karyotypes using InfoGenomeR
title_full	Integrative reconstruction of cancer genome karyotypes using InfoGenomeR
title_fullStr	Integrative reconstruction of cancer genome karyotypes using InfoGenomeR
title_full_unstemmed	Integrative reconstruction of cancer genome karyotypes using InfoGenomeR
title_sort	integrative reconstruction of cancer genome karyotypes using infogenomer
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/07eb649ab8d84331b7a259b6fb709d4e
work_keys_str_mv	AT yeonghunlee integrativereconstructionofcancergenomekaryotypesusinginfogenomer AT hyunjulee integrativereconstructionofcancergenomekaryotypesusinginfogenomer
_version_	1718382779912159232

Integrative reconstruction of cancer genome karyotypes using InfoGenomeR

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