Chromatin accessibility data sets show bias due to sequence specificity of the DNase I enzyme.

<h4>Background</h4>DNase I is an enzyme which cuts duplex DNA at a rate that depends strongly upon its chromatin environment. In combination with high-throughput sequencing (HTS) technology, it can be used to infer genome-wide landscapes of open chromatin regions. Using this technology,...

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Autores principales: Hashem Koohy, Thomas A Down, Tim J Hubbard
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/07f3562fbdd9490287ef1b6281a41eec
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