The Molecular Mechanisms of Allosteric Mutations Impairing MepR Repressor Function in Multidrug-Resistant Strains of <named-content content-type="genus-species">Staphylococcus aureus</named-content>
ABSTRACT Overexpression of the Staphylococcus aureus multidrug efflux pump MepA confers resistance to a wide variety of antimicrobials. mepA expression is controlled by MarR family member MepR, which represses mepA and autorepresses its own production. Mutations in mepR are a primary cause of mepA o...
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| Auteurs principaux: | , , , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
American Society for Microbiology
2013
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| Accès en ligne: | https://doaj.org/article/07f73ecbe7c84e91b1c2658cca5f9fe4 |
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