Profiling protein expression in circulating tumour cells using microfluidic western blotting

Circulating tumour cells (CTCs) are rare cells found in the blood of certain cancer patients. Here, the authors develop a cytometry tool that appends a microfluidic western blot to a CTC isolation workflow and apply it to profile a panel of proteins in single CTCs isolated from ER+ breast cancer pat...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Elly Sinkala, Elodie Sollier-Christen, Corinne Renier, Elisabet Rosàs-Canyelles, James Che, Kyra Heirich, Todd A. Duncombe, Julea Vlassakis, Kevin A. Yamauchi, Haiyan Huang, Stefanie S. Jeffrey, Amy E. Herr
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/07fbb330fecc4ed28810eb8735b09dd0
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:07fbb330fecc4ed28810eb8735b09dd0
record_format	dspace
spelling	oai:doaj.org-article:07fbb330fecc4ed28810eb8735b09dd02021-12-02T14:41:21ZProfiling protein expression in circulating tumour cells using microfluidic western blotting10.1038/ncomms146222041-1723https://doaj.org/article/07fbb330fecc4ed28810eb8735b09dd02017-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms14622https://doaj.org/toc/2041-1723Circulating tumour cells (CTCs) are rare cells found in the blood of certain cancer patients. Here, the authors develop a cytometry tool that appends a microfluidic western blot to a CTC isolation workflow and apply it to profile a panel of proteins in single CTCs isolated from ER+ breast cancer patients.Elly SinkalaElodie Sollier-ChristenCorinne RenierElisabet Rosàs-CanyellesJames CheKyra HeirichTodd A. DuncombeJulea VlassakisKevin A. YamauchiHaiyan HuangStefanie S. JeffreyAmy E. HerrNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Elly Sinkala Elodie Sollier-Christen Corinne Renier Elisabet Rosàs-Canyelles James Che Kyra Heirich Todd A. Duncombe Julea Vlassakis Kevin A. Yamauchi Haiyan Huang Stefanie S. Jeffrey Amy E. Herr Profiling protein expression in circulating tumour cells using microfluidic western blotting
description	Circulating tumour cells (CTCs) are rare cells found in the blood of certain cancer patients. Here, the authors develop a cytometry tool that appends a microfluidic western blot to a CTC isolation workflow and apply it to profile a panel of proteins in single CTCs isolated from ER+ breast cancer patients.
format	article
author	Elly Sinkala Elodie Sollier-Christen Corinne Renier Elisabet Rosàs-Canyelles James Che Kyra Heirich Todd A. Duncombe Julea Vlassakis Kevin A. Yamauchi Haiyan Huang Stefanie S. Jeffrey Amy E. Herr
author_facet	Elly Sinkala Elodie Sollier-Christen Corinne Renier Elisabet Rosàs-Canyelles James Che Kyra Heirich Todd A. Duncombe Julea Vlassakis Kevin A. Yamauchi Haiyan Huang Stefanie S. Jeffrey Amy E. Herr
author_sort	Elly Sinkala
title	Profiling protein expression in circulating tumour cells using microfluidic western blotting
title_short	Profiling protein expression in circulating tumour cells using microfluidic western blotting
title_full	Profiling protein expression in circulating tumour cells using microfluidic western blotting
title_fullStr	Profiling protein expression in circulating tumour cells using microfluidic western blotting
title_full_unstemmed	Profiling protein expression in circulating tumour cells using microfluidic western blotting
title_sort	profiling protein expression in circulating tumour cells using microfluidic western blotting
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/07fbb330fecc4ed28810eb8735b09dd0
work_keys_str_mv	AT ellysinkala profilingproteinexpressionincirculatingtumourcellsusingmicrofluidicwesternblotting AT elodiesollierchristen profilingproteinexpressionincirculatingtumourcellsusingmicrofluidicwesternblotting AT corinnerenier profilingproteinexpressionincirculatingtumourcellsusingmicrofluidicwesternblotting AT elisabetrosascanyelles profilingproteinexpressionincirculatingtumourcellsusingmicrofluidicwesternblotting AT jamesche profilingproteinexpressionincirculatingtumourcellsusingmicrofluidicwesternblotting AT kyraheirich profilingproteinexpressionincirculatingtumourcellsusingmicrofluidicwesternblotting AT toddaduncombe profilingproteinexpressionincirculatingtumourcellsusingmicrofluidicwesternblotting AT juleavlassakis profilingproteinexpressionincirculatingtumourcellsusingmicrofluidicwesternblotting AT kevinayamauchi profilingproteinexpressionincirculatingtumourcellsusingmicrofluidicwesternblotting AT haiyanhuang profilingproteinexpressionincirculatingtumourcellsusingmicrofluidicwesternblotting AT stefaniesjeffrey profilingproteinexpressionincirculatingtumourcellsusingmicrofluidicwesternblotting AT amyeherr profilingproteinexpressionincirculatingtumourcellsusingmicrofluidicwesternblotting
_version_	1718389912255856640

Profiling protein expression in circulating tumour cells using microfluidic western blotting

Ejemplares similares