Genetically engineered magnetic nanocages for cancer magneto-catalytic theranostics

The clinical application of magnetic hyperthermia therapy (MHT) is limited by the poor magnetic-to-thermal conversion efficiency of MHT agents. Here, the authors develop encapsulin-produced magnetic iron oxide nanocomposites (eMIONs) with excellent magnetic-heat capability and catalysis-triggered tu...

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Autores principales: Yang Zhang, Xiaoyong Wang, Chengchao Chu, Zijian Zhou, Biaoqi Chen, Xin Pang, Gan Lin, Huirong Lin, Yuxin Guo, En Ren, Peng Lv, Yesi Shi, Qingbing Zheng, Xiaohui Yan, Xiaoyuan Chen, Gang Liu
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/07fbdc0abb2d4e2db953b9c7d5286507
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spelling oai:doaj.org-article:07fbdc0abb2d4e2db953b9c7d52865072021-12-02T14:41:25ZGenetically engineered magnetic nanocages for cancer magneto-catalytic theranostics10.1038/s41467-020-19061-92041-1723https://doaj.org/article/07fbdc0abb2d4e2db953b9c7d52865072020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19061-9https://doaj.org/toc/2041-1723The clinical application of magnetic hyperthermia therapy (MHT) is limited by the poor magnetic-to-thermal conversion efficiency of MHT agents. Here, the authors develop encapsulin-produced magnetic iron oxide nanocomposites (eMIONs) with excellent magnetic-heat capability and catalysis-triggered tumor suppression ability to overcome the critical issues of MHT.Yang ZhangXiaoyong WangChengchao ChuZijian ZhouBiaoqi ChenXin PangGan LinHuirong LinYuxin GuoEn RenPeng LvYesi ShiQingbing ZhengXiaohui YanXiaoyuan ChenGang LiuNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yang Zhang
Xiaoyong Wang
Chengchao Chu
Zijian Zhou
Biaoqi Chen
Xin Pang
Gan Lin
Huirong Lin
Yuxin Guo
En Ren
Peng Lv
Yesi Shi
Qingbing Zheng
Xiaohui Yan
Xiaoyuan Chen
Gang Liu
Genetically engineered magnetic nanocages for cancer magneto-catalytic theranostics
description The clinical application of magnetic hyperthermia therapy (MHT) is limited by the poor magnetic-to-thermal conversion efficiency of MHT agents. Here, the authors develop encapsulin-produced magnetic iron oxide nanocomposites (eMIONs) with excellent magnetic-heat capability and catalysis-triggered tumor suppression ability to overcome the critical issues of MHT.
format article
author Yang Zhang
Xiaoyong Wang
Chengchao Chu
Zijian Zhou
Biaoqi Chen
Xin Pang
Gan Lin
Huirong Lin
Yuxin Guo
En Ren
Peng Lv
Yesi Shi
Qingbing Zheng
Xiaohui Yan
Xiaoyuan Chen
Gang Liu
author_facet Yang Zhang
Xiaoyong Wang
Chengchao Chu
Zijian Zhou
Biaoqi Chen
Xin Pang
Gan Lin
Huirong Lin
Yuxin Guo
En Ren
Peng Lv
Yesi Shi
Qingbing Zheng
Xiaohui Yan
Xiaoyuan Chen
Gang Liu
author_sort Yang Zhang
title Genetically engineered magnetic nanocages for cancer magneto-catalytic theranostics
title_short Genetically engineered magnetic nanocages for cancer magneto-catalytic theranostics
title_full Genetically engineered magnetic nanocages for cancer magneto-catalytic theranostics
title_fullStr Genetically engineered magnetic nanocages for cancer magneto-catalytic theranostics
title_full_unstemmed Genetically engineered magnetic nanocages for cancer magneto-catalytic theranostics
title_sort genetically engineered magnetic nanocages for cancer magneto-catalytic theranostics
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/07fbdc0abb2d4e2db953b9c7d5286507
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