Tetra-gel enables superior accuracy in combined super-resolution imaging and expansion microscopy
Abstract The accuracy of expansion microscopy (ExM) depends on the structural preservation of samples embedded in a hydrogel. However, it has been unknown to what extent gel embedding alters the molecular positions of individual labeled sites. Here, we quantified the accuracy of gel embedding by usi...
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Main Authors: | Hsuan Lee, Chih-Chieh Yu, Edward S. Boyden, Xiaowei Zhuang, Pallav Kosuri |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Subjects: | |
Online Access: | https://doaj.org/article/07fd9716e4d444bcb23396fa05e84b9c |
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