Pericardial Adipose Tissue–Derived Leptin Promotes Myocardial Apoptosis in High‐Fat Diet–Induced Obese Rats Through Janus Kinase 2/Reactive Oxygen Species/Na+/K+‐ATPase Signaling Pathway

Background Pathophysiologic mechanisms underlying cardiac structural and functional changes in obesity are complex and linked to adipocytokines released from pericardial adipose tissue (PAT) and cardiomyocyte apoptosis. Although leptin is involved in various pathological conditions, its role in para...

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Autores principales:	Ping Wang, Chaodi Luo, Danjun Zhu, Yan Song, Lifei Cao, Hui Luan, Lan Gao, Shuping Zheng, Hao Li, Gang Tian
Formato:	article
Lenguaje:	EN
Publicado:	Wiley 2021
Materias:	leptin myocardial apoptosis Na+/K+‐ATPase obesity paracrine pericardial adipose tissue Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/08013084feff492f963a9a6cb062a789
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Pericardial Adipose Tissue–Derived Leptin Promotes Myocardial Apoptosis in High‐Fat Diet–Induced Obese Rats Through Janus Kinase 2/Reactive Oxygen Species/Na+/K+‐ATPase Signaling Pathway

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