LncRNA XR_001779380 Primes Epithelial Cells for IFN-γ-Mediated Gene Transcription and Facilitates Age-Dependent Intestinal Antimicrobial Defense

Epithelial cells along the mucosal surface provide the front line of defense against luminal pathogen infection in the gastrointestinal tract. These epithelial cells represent an integral component of a highly regulated communication network that can transmit essential signals to cells in the under...

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Autores principales: Ai-Yu Gong, Yang Wang, Min Li, Xin-Tian Zhang, Silu Deng, Jessie M. Chen, Eugene Lu, Nicholas W. Mathy, Gislaine A. Martins, Juliane K. Strauss-Soukup, Xian-Ming Chen
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Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/0801779eeecf4115bddb57f5ae461f83
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spelling oai:doaj.org-article:0801779eeecf4115bddb57f5ae461f832021-11-03T21:52:35ZLncRNA XR_001779380 Primes Epithelial Cells for IFN-γ-Mediated Gene Transcription and Facilitates Age-Dependent Intestinal Antimicrobial Defense2150-751110.1128/mBio.02127-21https://doaj.org/article/0801779eeecf4115bddb57f5ae461f832021-10-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.02127-21https://doaj.org/toc/2150-7511 Epithelial cells along the mucosal surface provide the front line of defense against luminal pathogen infection in the gastrointestinal tract. These epithelial cells represent an integral component of a highly regulated communication network that can transmit essential signals to cells in the underlying intestinal mucosa that, in turn, serve as targets of mucosal immune mediators.Ai-Yu GongYang WangMin LiXin-Tian ZhangSilu DengJessie M. ChenEugene LuNicholas W. MathyGislaine A. MartinsJuliane K. Strauss-SoukupXian-Ming ChenAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 5 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Ai-Yu Gong
Yang Wang
Min Li
Xin-Tian Zhang
Silu Deng
Jessie M. Chen
Eugene Lu
Nicholas W. Mathy
Gislaine A. Martins
Juliane K. Strauss-Soukup
Xian-Ming Chen
LncRNA XR_001779380 Primes Epithelial Cells for IFN-γ-Mediated Gene Transcription and Facilitates Age-Dependent Intestinal Antimicrobial Defense
description Epithelial cells along the mucosal surface provide the front line of defense against luminal pathogen infection in the gastrointestinal tract. These epithelial cells represent an integral component of a highly regulated communication network that can transmit essential signals to cells in the underlying intestinal mucosa that, in turn, serve as targets of mucosal immune mediators.
format article
author Ai-Yu Gong
Yang Wang
Min Li
Xin-Tian Zhang
Silu Deng
Jessie M. Chen
Eugene Lu
Nicholas W. Mathy
Gislaine A. Martins
Juliane K. Strauss-Soukup
Xian-Ming Chen
author_facet Ai-Yu Gong
Yang Wang
Min Li
Xin-Tian Zhang
Silu Deng
Jessie M. Chen
Eugene Lu
Nicholas W. Mathy
Gislaine A. Martins
Juliane K. Strauss-Soukup
Xian-Ming Chen
author_sort Ai-Yu Gong
title LncRNA XR_001779380 Primes Epithelial Cells for IFN-γ-Mediated Gene Transcription and Facilitates Age-Dependent Intestinal Antimicrobial Defense
title_short LncRNA XR_001779380 Primes Epithelial Cells for IFN-γ-Mediated Gene Transcription and Facilitates Age-Dependent Intestinal Antimicrobial Defense
title_full LncRNA XR_001779380 Primes Epithelial Cells for IFN-γ-Mediated Gene Transcription and Facilitates Age-Dependent Intestinal Antimicrobial Defense
title_fullStr LncRNA XR_001779380 Primes Epithelial Cells for IFN-γ-Mediated Gene Transcription and Facilitates Age-Dependent Intestinal Antimicrobial Defense
title_full_unstemmed LncRNA XR_001779380 Primes Epithelial Cells for IFN-γ-Mediated Gene Transcription and Facilitates Age-Dependent Intestinal Antimicrobial Defense
title_sort lncrna xr_001779380 primes epithelial cells for ifn-γ-mediated gene transcription and facilitates age-dependent intestinal antimicrobial defense
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/0801779eeecf4115bddb57f5ae461f83
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