Probing the impact of sulfur/selenium/carbon linkages on prodrug nanoassemblies for cancer therapy

Prodrug-based self-assembled nanoparticles have emerged as an efficient drug delivery system (DDS) for cancer therapy. Here, the authors show that the type of bond in prodrug assemblies influences the efficiency of the DDS on several different levels.

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Bibliographic Details
Main Authors: Bingjun Sun, Cong Luo, Xuanbo Zhang, Mengran Guo, Mengchi Sun, Han Yu, Qin Chen, Wenqian Yang, Menglin Wang, Shiyi Zuo, Pengyu Chen, Qiming Kan, Haotian Zhang, Yongjun Wang, Zhonggui He, Jin Sun
Format: article
Language:EN
Published: Nature Portfolio 2019
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Online Access:https://doaj.org/article/080cae64d81641a5889836efc1dfe3d1
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Summary:Prodrug-based self-assembled nanoparticles have emerged as an efficient drug delivery system (DDS) for cancer therapy. Here, the authors show that the type of bond in prodrug assemblies influences the efficiency of the DDS on several different levels.